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Gene Set: D4 : TTD - Exemestane

Collection D4 : TTD
Chemical Name Exemestane ( From PubChem : EXEMESTANE )
FDA NPC WHO Indian Australia China Traditional
Herbal		 Clinical
Trail
ApprovedNotNotNotNotNotNotNot
Molecular
Weight		 Hydrogen Bond
Donor Count		 Hydrogen Bond
Acceptor Count		 cLogP Lipinski Rule
296.403 g/mol 0 2 4.0295 True
Structure
InChI InChI=1S/C20H24O2/c1-12-10-14-15-4-5-18(22)20(15,3)9-7-16(14)19(2)8-6-13(21)11-17(12)19/h6,8,11,14-16H,1,4-5,7,9-10H2,2-3H3/t14-,15-,16-,19+,20-/m0/s1
InChIKey BFYIZQONLCFLEV-DAELLWKTSA-N
Links

Gene (5 / 11)


⊖ Less
Source Type Unit Value Gene PMID Assay Other
TTDInhibitorCYP19A1Successful target
TTDDrug(s)CYP19A1Successful target
PubChem Potency-Replicate_1uM0.030AR-GI(Protien) :
PubChem Ratio Potency (uM)uM0.601AR-GI(Protien) :
PubChem Potency-Replicate_1uM0.042CYP19A1-GI(Protien) :
PubChem NoneuMCYP19A1-GI(Protien) :
PubChem Potency-Replicate_1uM8.413ESR1-GI(Protien) :
PubChem Ratio Potency (uM)uM2.033NFE2L2-GI(Protien) :
PubChem Potency-Replicate_1uM2.660NFE2L2-GI(Protien) :
PubChem PotencyuM8.414TDP1-GI(Protien) :
PubChem PotencyuM16.360TDP1-GI(Protien) :
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