Tan Lab | DSigDB

Gene Set: D4 : TTD - Estrone

Collection

D4 : TTD

Chemical Name

Estrone ( From PubChem : ESTRONE )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Approved	Not	Not	Not	Not	Not	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
270.366 g/mol	1	2	3.8174	True

Structure

InChI

InChI=1S/C18H22O2/c1-18-9-8-14-13-5-3-12(19)10-11(13)2-4-15(14)16(18)6-7-17(18)20/h3,5,10,14-16,19H,2,4,6-9H2,1H3/t14-,15-,16+,18+/m1/s1

InChIKey

Links

Gene (4 / 18)

⊖ Less

Source	Type	Unit	Value	Gene	PMID	Other
TTD	Agonist			ESR1		Successful target
TTD	Drug(s)			ESR1		Successful target
PubChem	Potency-Replicate_1	uM	1.725	AR	-	GI(Protien) :
PubChem	Ratio Potency (uM)	uM	1.952	AR	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	4.216	AR	-	GI(Protien) :
PubChem	Ratio Potency (uM)	uM	4.592	AR	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	4.772	AR	-	GI(Protien) :
PubChem	AR Potency (uM)	uM	10.078	AR	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	0.001	ESR1	-	GI(Protien) :
PubChem	Ratio Potency (uM)	uM	0.002	ESR1	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	0.004	ESR1	-	GI(Protien) :
PubChem	Ratio Potency (uM)	uM	0.006	ESR1	-	GI(Protien) :
PubChem	Potency	uM	0.011	ESR1	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM		ESR1	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	39.811	NR1I2	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	3.894	NR3C1	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	7.562	NR3C1	-	GI(Protien) :
PubChem	None	uM		NR3C1	-	GI(Protien) :

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