Tan Lab | DSigDB

Gene Set: D4 : TTD - Estriol

Collection

D4 : TTD

Chemical Name

Estriol ( From PubChem : ESTRIOL )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Not	Not	Not	Not	Not	Not	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
288.381 g/mol	3	3	2.58	True

Structure

InChI

InChI=1S/C18H24O3/c1-18-7-6-13-12-5-3-11(19)8-10(12)2-4-14(13)15(18)9-16(20)17(18)21/h3,5,8,13-17,19-21H,2,4,6-7,9H2,1H3/t13-,14-,15+,16-,17+,18+/m1/s1

InChIKey

PROQIPRRNZUXQM-ZXXIGWHRSA-N

Links

Gene (4 / 17)

⊖ Less

Source	Type	Unit	Value	Gene	PMID	Other
TTD	Agonist			ESR1		Successful target
TTD	Drug(s)			ESR1		Successful target
PubChem	Potency-Replicate_1	uM	6.917	AR	-	GI(Protien) :
PubChem	Ratio Potency (uM)	uM	13.801	AR	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	18.996	AR	-	GI(Protien) :
PubChem	Ratio Potency (uM)	uM	20.122	AR	-	GI(Protien) :
PubChem	AR Potency (uM)	uM	54.483	AR	-	GI(Protien) :
PubChem	None	uM		CACNA1H	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	0.001	ESR1	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	0.002	ESR1	-	GI(Protien) :
PubChem	Ratio Potency (uM)	uM	0.002	ESR1	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	0.002	ESR1	-	GI(Protien) :
PubChem	Ratio Potency (uM)	uM	0.004	ESR1	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM		ESR1	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	11.986	NR3C1	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	38.895	NR3C1	-	GI(Protien) :
PubChem	None	uM		NR3C1	-	GI(Protien) :

Download gene sets

gmt, text, Detailed text