| Collection |
D4 : TTD |
| Chemical Name |
EPZ-5676 ( From PubChem : E P Z - 5 6 7 6 ) |
| FDA |
NPC |
WHO |
Indian |
Australia |
China |
Traditional
Herbal |
Clinical
Trail |
| Not | Not | Not | Not | Not | Not | Not | Not |
|
Molecular
Weight |
Hydrogen Bond
Donor Count |
Hydrogen Bond
Acceptor Count |
cLogP |
Lipinski Rule |
| 562.706 g/mol |
4 |
10 |
3.9045 |
False(3/4) |
|
| Structure |
|
| InChI |
I n C h I = 1 S / C 3 0 H 4 2 N 8 O 3 / c 1 - 1 6 ( 2 ) 3 7 ( 1 3 - 2 2 - 2 5 ( 3 9 ) 2 6 ( 4 0 ) 2 9 ( 4 1 - 2 2 ) 3 8 - 1 5 - 3 4 - 2 4 - 2 7 ( 3 1 ) 3 2 - 1 4 - 3 3 - 2 8 ( 2 4 ) 3 8 ) 1 9 - 1 0 - 1 7 ( 1 1 - 1 9 ) 6 - 9 - 2 3 - 3 5 - 2 0 - 8 - 7 - 1 8 ( 3 0 ( 3 , 4 ) 5 ) 1 2 - 2 1 ( 2 0 ) 3 6 - 2 3 / h 7 - 8 , 1 2 , 1 4 - 1 7 , 1 9 , 2 2 , 2 5 - 2 6 , 2 9 , 3 9 - 4 0 H , 6 , 9 - 1 1 , 1 3 H 2 , 1 - 5 H 3 , ( H , 3 5 , 3 6 ) ( H 2 , 3 1 , 3 2 , 3 3 ) / t 1 7 - , 1 9 - , 2 2 - , 2 5 - , 2 6 - , 2 9 - / m 1 / s 1 |
| InChIKey |
L X F O L M Y K S Y S Z Q S - Y K P Y G O B T S A - N
|
| Links |
|
Gene
(1 /
1)
⊖ Less
|
| Source | Type | Unit | Value | Gene | PMID | Assay | Other | | TTD | Drug(s) | DOT1L | | | Clinical trial target |
|
| Download gene sets |
gmt, text, Detailed text
|
