Tan Lab | DSigDB

Gene Set: D4 : TTD - Enzastaurin

Collection

D4 : TTD

Chemical Name

Enzastaurin ( From PubChem : ENZASTAURIN )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Not	Not	Not	Not	Not	Not	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
515.605 g/mol	1	7	5.199	False(2/4)

Structure

InChI

InChI=1S/C32H29N5O2/c1-35-19-25(23-9-2-4-11-27(23)35)29-30(32(39)34-31(29)38)26-20-37(28-12-5-3-10-24(26)28)22-13-16-36(17-14-22)18-21-8-6-7-15-33-21/h2-12,15,19-20,22H,13-14,16-18H2,1H3,(H,34,38,39)

InChIKey

AXRCEOKUDYDWLF-UHFFFAOYSA-N

Links

Gene (9 / 21)

⊖ Less

Source	Type	Unit	Value	Gene	PMID	Other
TTD	Multitarget			AKT1		Clinical trial target
TTD	Inhibitor			AKT1		Clinical trial target
TTD	Drug(s)			AKT1		Clinical trial target
TTD	Multitarget			AKT2		Clinical trial target
TTD	Inhibitor			AKT2		Clinical trial target
TTD	Drug(s)			AKT2		Clinical trial target
TTD	Multitarget			AKT3		Clinical trial target
TTD	Inhibitor			AKT3		Clinical trial target
TTD	Drug(s)			AKT3		Clinical trial target
TTD	Multitarget			GSK3B		Clinical trial target
TTD	Inhibitor			GSK3B		Clinical trial target
TTD	Drug(s)			GSK3B		Clinical trial target
TTD	Multitarget			PRKCB		Clinical trial target
TTD	Inhibitor			PRKCB		Clinical trial target
TTD	Drug(s)			PRKCB		Clinical trial target
PubChem	Potency-Replicate_1	uM	5.354	ESR1	-	GI(Protien) :
PubChem	Ratio Potency (uM)	uM	6.363	ESR1	-	GI(Protien) :
PubChem	None	uM		NR1H4	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	1.345	NR3C1	-	GI(Protien) :
PubChem	None	uM		NR3C1	-	GI(Protien) :
PubChem	None	uM		PPARG	-	GI(Protien) :

Download gene sets

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