Tan Lab | DSigDB

Gene Set: D4 : TTD - EMBELIN

Collection

D4 : TTD

Chemical Name

EMBELIN ( From PubChem : EMBELIN )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Not	Not	Not	Not	Not	Not	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
294.386 g/mol	2	4	4.3131	True

Structure

InChI

InChI=1S/C17H26O4/c1-2-3-4-5-6-7-8-9-10-11-13-16(20)14(18)12-15(19)17(13)21/h12,18,21H,2-11H2,1H3

InChIKey

IRSFLDGTOHBADP-UHFFFAOYSA-N

Links

Gene (26 / 50)

⊖ Less

Source	Type	Unit	Value	Gene	PMID	Other
TTD	Inhibitor			XIAP		Clinical trial target
PubChem	Potency	uM	19.953	ALDH1A1	-	GI(Protien) :
PubChem	Potency	uM	23.756	ALDH1A1	-	GI(Protien) :
PubChem	Potency	uM	8.912	ALOX12	-	GI(Protien) :
PubChem	Potency	uM	5.012	ALOX15	-	GI(Protien) :
PubChem	None	uM		BCL2L1	-	GI(Protien) :
PubChem	None	uM		CRHBP	-	GI(Protien) :
PubChem	None	uM		CRHR2	-	GI(Protien) :
PubChem	Potency	uM	25.119	CYP2C9	-	GI(Protien) :
PubChem	Potency	uM	1.995	CYP2D6	-	GI(Protien) :
PubChem	None	uM		CYP2D6	-	GI(Protien) :
PubChem	None	uM		FASN	-	GI(Protien) :
PubChem	None	uM		GSTO1	-	GI(Protien) :
PubChem	None	uM		GSTO1	-	GI(Protien) :
PubChem	Potency	uM	14.125	HPGD	-	GI(Protien) :
PubChem	Potency	uM	10.000	MAPT	-	GI(Protien) :
PubChem	Potency	uM	19.953	MAPT	-	GI(Protien) :
PubChem	None	uM		MAPT	-	GI(Protien) :
PubChem	None	uM		MC4R	-	GI(Protien) :
PubChem	None	uM		MCL1	-	GI(Protien) :
PubChem	None	uM		MCL1	-	GI(Protien) :
PubChem	None	uM		PAFAH2	-	GI(Protien) :
PubChem	None	uM		PAFAH2	-	GI(Protien) :
PubChem	Potency	uM	28.184	PIN1	-	GI(Protien) :
PubChem	Potency	uM	29.935	PLK1	-	GI(Protien) :
PubChem	None	uM		PPP1CA	-	GI(Protien) :
PubChem	None	uM		PPP1CA	-	GI(Protien) :
PubChem	None	uM		PTGER2	-	GI(Protien) :
PubChem	None	uM		SENP8	-	GI(Protien) :
PubChem	Potency	uM	12.589	TP53	-	GI(Protien) :
PubChem	Potency	uM	12.589	TP53	-	GI(Protien) :
ChEMBL	Potency	nM	23755.800	ALDH1A1	-	Target : CHEMBL3577
ChEMBL	Potency	nM	19952.600	ALDH1A1	-	Target : CHEMBL3577
ChEMBL	Potency	nM	8912.500	ALOX12	-	Target : CHEMBL3687
ChEMBL	Potency	nM	5011.900	ALOX15	-	Target : CHEMBL2903
ChEMBL	Potency	nM	31622.800	ALOX15B	-	Target : CHEMBL2457
ChEMBL	Potency	nM	25118.900	CYP2C9	-	Target : CHEMBL3397
ChEMBL	AC50	nM	1995.260	CYP2D6	-	Target : CHEMBL289
ChEMBL	Potency	nM	1995.300	CYP2D6	-	Target : CHEMBL289
ChEMBL	Potency	nM	14125.400	HPGD	-	Target : CHEMBL1293255
ChEMBL	Potency	nM	3162.300	HSD17B10	-	Target : CHEMBL4159
ChEMBL	Potency	nM	28183.800	KDM4A	-	Target : CHEMBL5896
ChEMBL	Potency	nM	39810.700	KDM4A	-	Target : CHEMBL5896
ChEMBL	Potency	nM	19952.600	KDM4E	-	Target : CHEMBL1293226
ChEMBL	Potency	nM	4466.800	KDM4E	-	Target : CHEMBL1293226
ChEMBL	Potency	nM	11220.200	MAPT	-	Target : CHEMBL1293224
ChEMBL	Potency	nM	19952.600	MAPT	-	Target : CHEMBL1293224
ChEMBL	Potency	nM	10000.000	MAPT	-	Target : CHEMBL1293224
ChEMBL	Potency	nM	12589.300	TP53	-	Target : CHEMBL4096
ChEMBL	Potency	nM	12589.300	TP53	-	Target : CHEMBL4096

Download gene sets

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