DSigDB

Drug SIGnatures DataBase Collection of Annoated Drug / Compound Gene Sets

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Gene Set: D4 : TTD - 5'-(N-ethyl-N-isopropyl)amiloride

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Collection	D4 : TTD
Chemical Name	5'-(N-ethyl-N-isopropyl)amiloride ( From PubChem : EIPA )
FDA NPC WHO Indian Australia China Traditional Herbal Clinical Trail Not Not Not Not Not Not Not Not
Molecular Weight Hydrogen Bond Donor Count Hydrogen Bond Acceptor Count cLogP Lipinski Rule 299.76 g/mol 3 8 2.3423 True
Structure
InChI	InChI=1S/C11H18ClN7O/c1-4-19(5(2)3)9-7(12)16-6(8(13)17-9)10(20)18-11(14)15/h5H,4H2,1-3H3,(H2,13,17)(H4,14,15,18,20)
InChIKey	QDERNBXNXJCIQK-UHFFFAOYSA-N
Links
Gene (7 / 16) ⊖ Less	Source Type Unit Value Gene PMID Assay Other TTD Inhibitor SLC9A1 Research target PubChem None uM CYP1A2 - GI(Protien) : PubChem None uM CYP1A2 - GI(Protien) : PubChem None uM MRGPRX1 - GI(Protien) : PubChem None uM MRGPRX1 - GI(Protien) : PubChem EC50 uM 9.569 OPRD1 - GI(Protien) : PubChem None uM OPRD1 - GI(Protien) : PubChem None uM OPRD1 - GI(Protien) : PubChem EC50 uM 9.569 OPRM1 - GI(Protien) : PubChem None uM OPRM1 - GI(Protien) : PubChem None uM OPRM1 - GI(Protien) : PubChem AC50_uM uM 20.940 PAX8 - GI(Protien) : PubChem None uM PAX8 - GI(Protien) : PubChem Potency uM 7.308 TDP1 - GI(Protien) : PubChem Potency uM 20.596 TDP1 - GI(Protien) : ChEMBL AC50 nM 1995.260 CYP1A2 - Target : CHEMBL3356
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