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Drug SIGnatures DataBase Collection of Annoated Drug / Compound Gene Sets

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Gene Set: D4 : TTD - ECONAZOLE NITRATE

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Collection	D4 : TTD
Chemical Name	ECONAZOLE NITRATE ( From PubChem : ECONAZOLE NITRATE )
FDA NPC WHO Indian Australia China Traditional Herbal Clinical Trail Approved Not Not Approved Not Approved Not Not
Molecular Weight Hydrogen Bond Donor Count Hydrogen Bond Acceptor Count cLogP Lipinski Rule 444.696 g/mol 1 3 5.9769 False(3/4)
Structure
InChI	InChI=1S/C18H15Cl3N2O.HNO3/c19-14-3-1-13(2-4-14)11-24-18(10-23-8-7-22-12-23)16-6-5-15(20)9-17(16)21;2-1(3)4/h1-9,12,18H,10-11H2;(H,2,3,4)
InChIKey	DDXORDQKGIZAME-UHFFFAOYSA-N
Links
Gene (26 / 62) ⊖ Less	Source Type Unit Value Gene PMID Assay Other TTD Inhibitor NPY1R Clinical trial target TTD Inhibitor NPY2R Clinical trial target PubChem None uM ABCB1 - GI(Protien) : PubChem AhR Potency (uM) uM 3.813 AHR - GI(Protien) : PubChem Potency-Replicate_1 uM 23.915 AR - GI(Protien) : PubChem Potency-Replicate_1 uM 25.481 AR - GI(Protien) : PubChem AR Potency (uM) uM 28.180 AR - GI(Protien) : PubChem Potency-Replicate_1 uM 29.849 AR - GI(Protien) : PubChem Potency-Replicate_1 uM 54.261 AR - GI(Protien) : PubChem Potency uM 39.811 ATXN2 - GI(Protien) : PubChem Potency uM 25.119 BAZ2B - GI(Protien) : PubChem Potency-Replicate_1 uM 0.068 CYP19A1 - GI(Protien) : PubChem Potency-Replicate_1 uM 0.255 CYP19A1 - GI(Protien) : PubChem Potency-Replicate_1 uM 0.531 CYP19A1 - GI(Protien) : PubChem None uM CYP19A1 - GI(Protien) : PubChem Potency uM 0.398 CYP3A4 - GI(Protien) : PubChem ER Potency (uM) uM 17.780 ESR1 - GI(Protien) : PubChem Potency-Replicate_1 uM 23.710 ESR1 - GI(Protien) : PubChem ER Potency (uM) uM 52.218 ESR1 - GI(Protien) : PubChem Potency-Replicate_1 uM 60.882 ESR1 - GI(Protien) : PubChem None uM GNA15 - GI(Protien) : PubChem AC50_uM uM 0.267 HSP90AA1 - GI(Protien) : PubChem Ratio Potency (uM) uM 19.569 HSPB1 - GI(Protien) : PubChem Ratio Potency (uM) uM 28.824 HSPB1 - GI(Protien) : PubChem Ratio Potency (uM) uM 30.778 HSPB1 - GI(Protien) : PubChem Potency uM 7.080 KCNH2 GI(Protien) : PubChem Potency uM 7.080 KCNH2 GI(Protien) : PubChem None uM KCNQ1 - GI(Protien) : PubChem Potency uM 28.184 MAPK1 - GI(Protien) : PubChem None uM MCHR1 - GI(Protien) : PubChem None uM NPBWR1 - GI(Protien) : PubChem None uM NPBWR1 - GI(Protien) : PubChem IC50 uM 5.146 NPY1R - GI(Protien) : PubChem IC50 uM 8.024 NPY2R - GI(Protien) : PubChem None uM NPY2R - GI(Protien) : PubChem None uM NPY2R - GI(Protien) : PubChem Ratio Potency (uM) uM 14.122 NR1H4 - GI(Protien) : PubChem Ratio Potency (uM) uM 15.011 NR1H4 - GI(Protien) : PubChem Potency-Replicate_1 uM 23.708 NR1H4 - GI(Protien) : PubChem Ratio Potency (uM) uM 29.057 NR1H4 - GI(Protien) : PubChem Ratio Potency (uM) uM 29.847 PPARD - GI(Protien) : PubChem Ratio Potency (uM) uM 32.602 PPARD - GI(Protien) : PubChem Ratio Potency (uM) uM 51.257 PPARD - GI(Protien) : PubChem None uM PPP1CA - GI(Protien) : PubChem None uM PPP1CA - GI(Protien) : PubChem None uM TAAR1 - GI(Protien) : PubChem Potency uM 16.360 TDP1 - GI(Protien) : PubChem Potency uM 16.789 TDP1 - GI(Protien) : PubChem Potency uM 18.837 TDP1 - GI(Protien) : PubChem Potency uM 20.596 TDP1 - GI(Protien) : PubChem Potency uM 23.109 TDP1 - GI(Protien) : PubChem Potency uM 15.849 TP53 - GI(Protien) : PubChem None uM UBE2N - GI(Protien) : PubChem Potency-Replicate_1 uM 19.420 VDR - GI(Protien) : PubChem Potency-Replicate_1 uM 36.287 VDR - GI(Protien) : PubChem Potency uM 39.811 VDR - GI(Protien) : ChEMBL Potency nM 25118.900 BAZ2B - Target : CHEMBL1741220 ChEMBL Potency nM 398.100 CYP3A4 - Target : CHEMBL340 ChEMBL Potency nM 28183.800 MAPK1 - Target : CHEMBL4040 ChEMBL IC50 nM 5146.000 NPY1R - Target : CHEMBL4777 ChEMBL IC50 nM 8024.000 NPY2R - Target : CHEMBL4018 ChEMBL Potency nM 15848.900 TP53 - Target : CHEMBL4096
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