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Gene Set: D4 : TTD - Ebselen

Collection D4 : TTD
Chemical Name Ebselen ( From PubChem : EBSELEN )
FDA NPC WHO Indian Australia China Traditional
Herbal		 Clinical
Trail
NotNotNotNotNotNotNotNot
Molecular
Weight		 Hydrogen Bond
Donor Count		 Hydrogen Bond
Acceptor Count		 cLogP Lipinski Rule
274.177 g/mol 0 2 2.0477 True
Structure
InChI InChI=1S/C13H9NOSe/c15-13-11-8-4-5-9-12(11)16-14(13)10-6-2-1-3-7-10/h1-9H
InChIKey DYEFUKCXAQOFHX-UHFFFAOYSA-N
Links

Gene (68 / 163)


⊖ Less
Source Type Unit Value Gene PMID Assay Other
TTDDrug(s)ALBSuccessful target
PubChem IC50uM1.101ABHD5-GI(Protien) :
PubChem IC50uM3.410ABHD5-GI(Protien) :
PubChem NoneuMABHD5-GI(Protien) :
PubChem NoneuMABHD5-GI(Protien) :
PubChem NoneuMABHD5-GI(Protien) :
PubChem NoneuMABHD5-GI(Protien) :
PubChem PotencyuM0.126ALDH1A1-GI(Protien) :
PubChem PotencyuM0.224ALDH1A1-GI(Protien) :
PubChem PotencyuM0.447ALDH1A1-GI(Protien) :
PubChem PotencyuM2.512ALOX12-GI(Protien) :
PubChem PotencyuM3.162ALOX12-GI(Protien) :
PubChem PotencyuM0.063ALOX15-GI(Protien) :
PubChem PotencyuM0.398ALOX15-GI(Protien) :
PubChem IC50_MICROMuM1.524ARRB1-GI(Protien) :
PubChem NoneuMARRB1-GI(Protien) :
PubChem NoneuMARRB1-GI(Protien) :
PubChem NoneuMARRB1-GI(Protien) :
PubChem PotencyuM1.413BAZ2B-GI(Protien) :
PubChem PotencyuM25.119CBX1-GI(Protien) :
PubChem NoneuMCTDSP1-GI(Protien) :
PubChem Potency-Replicate_1uM29.849CYP19A1-GI(Protien) :
PubChem NoneuMCYP1A2-GI(Protien) :
PubChem PotencyuM0.126CYP2C19-GI(Protien) :
PubChem PotencyuM1.585CYP2C19-GI(Protien) :
PubChem PotencyuM0.079CYP2C9-GI(Protien) :
PubChem PotencyuM1.000CYP2C9-GI(Protien) :
PubChem PotencyuM1.000CYP2D6-GI(Protien) :
PubChem PotencyuM10.000CYP2D6-GI(Protien) :
PubChem PotencyuM3.981CYP3A4-GI(Protien) :
PubChem PotencyuM25.119CYP3A4-GI(Protien) :
PubChem NoneuMDLD-GI(Protien) :
PubChem PotencyuM0.071EHMT2-GI(Protien) :
PubChem PotencyuM0.501EHMT2-GI(Protien) :
PubChem PotencyuM1.413EHMT2-GI(Protien) :
PubChem Absolute IC50uM1.150EIF4G1-GI(Protien) :
PubChem NoneuMEIF4G1-GI(Protien) :
PubChem NoneuMERAP1-GI(Protien) :
PubChem PotencyuM79.433FEN1-GI(Protien) :
PubChem IC50_MeanuM13.200G6PD-GI(Protien) :
PubChem PotencyuM22.387GBA-GI(Protien) :
PubChem PotencyuM14.125GCK-GI(Protien) :
PubChem PotencyuM14.125GCKR-GI(Protien) :
PubChem PotencyuM25.119GLA-GI(Protien) :
PubChem PotencyuM2.818GLS-GI(Protien) :
PubChem PotencyuM6.310GLS-GI(Protien) :
PubChem PotencyuM18.356GMNN-GI(Protien) :
PubChem PotencyuM12.589GNAI1-GI(Protien) :
PubChem NoneuMGNAI1-GI(Protien) :
PubChem NoneuMGPR183-GI(Protien) :
PubChem NoneuMHKDC1-GI(Protien) :
PubChem NoneuMHKDC1-GI(Protien) :
PubChem NoneuMHNF4A-GI(Protien) :
PubChem PotencyuM0.355HPGD-GI(Protien) :
PubChem PotencyuM0.631HPGD-GI(Protien) :
PubChem PotencyuM0.708HPGD-GI(Protien) :
PubChem NoneuMIDE-GI(Protien) :
PubChem NoneuMIDE-GI(Protien) :
PubChem PotencyuM23.109IDH1-GI(Protien) :
PubChem NoneuMIL1B-GI(Protien) :
PubChem NoneuMITGA4-GI(Protien) :
PubChem PotencyuM0.251KAT2A-GI(Protien) :
PubChem PotencyuM0.355KAT2A-GI(Protien) :
PubChem PotencyuM0.398KAT2A-GI(Protien) :
PubChem PotencyuM0.794KAT2A-GI(Protien) :
PubChem NoneuMMDM2-GI(Protien) :
PubChem NoneuMMDM4-GI(Protien) :
PubChem PotencyuM2.994MPHOSPH8-GI(Protien) :
PubChem PotencyuM5.012MPHOSPH8-GI(Protien) :
PubChem IC50_MeanuM0.190MPI-GI(Protien) :
PubChem IC50uMMPI-GI(Protien) :
PubChem NoneuMMRGPRX1-GI(Protien) :
PubChem Absolute IC50uM0.390NCF1-GI(Protien) :
PubChem NoneuMNCF1-GI(Protien) :
PubChem NoneuMPABPC1-GI(Protien) :
PubChem NoneuMPADI4-GI(Protien) :
PubChem NoneuMPADI4-GI(Protien) :
PubChem IC50_MeanuM0.111PHOSPHO1-GI(Protien) :
PubChem IC50uMPHOSPHO1-GI(Protien) :
PubChem PotencyuM5.799PKM-GI(Protien) :
PubChem PotencyuM6.310PKM-GI(Protien) :
PubChem PotencyuM10.000PKM-GI(Protien) :
PubChem IC50uM3.410PLIN1-GI(Protien) :
PubChem NoneuMPLIN1-GI(Protien) :
PubChem IC50uM1.101PLIN5-GI(Protien) :
PubChem NoneuMPLIN5-GI(Protien) :
PubChem NoneuMPLIN5-GI(Protien) :
PubChem NoneuMPLIN5-GI(Protien) :
PubChem PotencyuM2.994PLK1-GI(Protien) :
PubChem IC50_MeanuM0.672PMM2-GI(Protien) :
PubChem PotencyuM3.162POLB-GI(Protien) :
PubChem NoneuMPRMT1-GI(Protien) :
PubChem NoneuMPTGER2-GI(Protien) :
PubChem PotencyuM12.589RGS12-GI(Protien) :
PubChem NoneuMRGS12-GI(Protien) :
PubChem PotencyuM0.670RGS4-GI(Protien) :
PubChem NoneuMSENP6-GI(Protien) :
PubChem NoneuMSENP7-GI(Protien) :
PubChem NoneuMSENP8-GI(Protien) :
PubChem NoneuMSTK33-GI(Protien) :
PubChem NoneuMTAAR1-GI(Protien) :
PubChem PotencyuM1.413TDP1-GI(Protien) :
PubChem PotencyuM2.512TDP1-GI(Protien) :
PubChem PotencyuM3.264TDP1-GI(Protien) :
PubChem PotencyuM3.264TDP1-GI(Protien) :
PubChem PotencyuM4.467TDP1-GI(Protien) :
PubChem PotencyuM5.012TDP1-GI(Protien) :
PubChem PotencyuM6.684TDP1-GI(Protien) :
PubChem PotencyuM8.414TDP1-GI(Protien) :
PubChem NoneuMTLR9-GI(Protien) :
PubChem PotencyuM2.818VDR-GI(Protien) :
PubChem PotencyuM7.080VDR-GI(Protien) :
PubChem PotencyuM7.943VDR-GI(Protien) :
PubChem PotencyuM17.783VDR-GI(Protien) :
ChEMBLPotencynM125.900ALDH1A1
-Target : CHEMBL3577
ChEMBLPotencynM446.700ALDH1A1
-Target : CHEMBL3577
ChEMBLPotencynM223.900ALDH1A1
-Target : CHEMBL3577
ChEMBLPotencynM3162.300ALOX12
-Target : CHEMBL3687
ChEMBLPotencynM2511.900ALOX12
-Target : CHEMBL3687
ChEMBLPotencynM63.100ALOX15
-Target : CHEMBL2903
ChEMBLPotencynM398.100ALOX15
-Target : CHEMBL2903
ChEMBLPotencynM501.200ALOX15B
-Target : CHEMBL2457
ChEMBLPotencynM631.000ALOX15B
-Target : CHEMBL2457
ChEMBLPotencynM1412.500BAZ2B
-Target : CHEMBL1741220
ChEMBLPotencynM25118.900CBX1
-Target : CHEMBL1741193
ChEMBLPotencynM125.900CYP2C19
-Target : CHEMBL3622
ChEMBLPotencynM1584.900CYP2C19
-Target : CHEMBL3622
ChEMBLPotencynM79.400CYP2C9
-Target : CHEMBL3397
ChEMBLPotencynM1000.000CYP2C9
-Target : CHEMBL3397
ChEMBLPotencynM1000.000CYP2D6
-Target : CHEMBL289
ChEMBLPotencynM10000.000CYP2D6
-Target : CHEMBL289
ChEMBLPotencynM3981.100CYP3A4
-Target : CHEMBL340
ChEMBLPotencynM25118.900CYP3A4
-Target : CHEMBL340
ChEMBLPotencynM70.800EHMT2
-Target : CHEMBL6032
ChEMBLPotencynM501.200EHMT2
-Target : CHEMBL6032
ChEMBLPotencynM1412.500EHMT2
-Target : CHEMBL6032
ChEMBLPotencynM22387.200GBA
-Target : CHEMBL2179
ChEMBLPotencynM25118.900GLA
-Target : CHEMBL2524
ChEMBLPotencynM707.900HPGD
-Target : CHEMBL1293255
ChEMBLPotencynM354.800HPGD
-Target : CHEMBL1293255
ChEMBLPotencynM631.000HPGD
-Target : CHEMBL1293255
ChEMBLPotencynM316.200HSD17B10
-Target : CHEMBL4159
ChEMBLPotencynM2511.900HSD17B10
-Target : CHEMBL4159
ChEMBLPotencynM794.300HSD17B10
-Target : CHEMBL4159
ChEMBLPotencynM3162.300HSD17B10
-Target : CHEMBL4159
ChEMBLPotencynM3981.100HSD17B10
-Target : CHEMBL4159
ChEMBLPotencynM398.100KAT2A
-Target : CHEMBL5501
ChEMBLPotencynM251.200KAT2A
-Target : CHEMBL5501
ChEMBLPotencynM794.300KAT2A
-Target : CHEMBL5501
ChEMBLPotencynM354.800KAT2A
-Target : CHEMBL5501
ChEMBLPotencynM8912.500KDM4A
-Target : CHEMBL5896
ChEMBLPotencynM6309.600KDM4E
-Target : CHEMBL1293226
ChEMBLPotencynM1258.900KDM4E
-Target : CHEMBL1293226
ChEMBLPotencynM398.100KDM4E
-Target : CHEMBL1293226
ChEMBLPotencynM5011.900MPHOSPH8
-Target : CHEMBL1741210
ChEMBLPotencynM2993.500MPHOSPH8
-Target : CHEMBL1741210
ChEMBLIC50nM190.000MPI
-Target : CHEMBL2758
ChEMBLIC50nM111.000PHOSPHO1
-Target : CHEMBL6113
ChEMBLPotencynM6309.600PKM
-Target : CHEMBL1075189
ChEMBLPotencynM5798.800PKM
-Target : CHEMBL1075189
ChEMBLPotencynM10000.000PKM
-Target : CHEMBL1075189
ChEMBLIC50nM672.000PMM2
-Target : CHEMBL1741162
ChEMBLPotencynM3162.300POLB
-Target : CHEMBL2392
Download gene sets gmt, text, Detailed text
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Aurora, CO 80045, USA

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