Tan Lab | DSigDB

Gene Set: D4 : TTD - E-64

Collection

D4 : TTD

Chemical Name

E-64 ( From PubChem : E-64 )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Not	Not	Not	Not	Not	Not	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
357.405 g/mol	5	10	0.7215	True

Structure

InChI

InChI=1S/C15H27N5O5/c1-8(2)7-9(20-13(22)10-11(25-10)14(23)24)12(21)18-5-3-4-6-19-15(16)17/h8-11H,3-7H2,1-2H3,(H,18,21)(H,20,22)(H,23,24)(H4,16,17,19)/t9-,10-,11-/m0/s1

InChIKey

LTLYEAJONXGNFG-DCAQKATOSA-N

Links

Gene (4 / 8)

⊖ Less

Source	Type	Unit	Value	Gene	PMID	Other
TTD	Inhibitor			CTSS		Discontinued target
PubChem	IC50 mean	uM	0.012	CTSB	-	GI(Protien) :
PubChem	None	uM		CTSB	-	GI(Protien) :
PubChem	IC50 mean	uM	0.020	CTSL	-	GI(Protien) :
PubChem	IC50 mean	uM	0.004	CTSS	-	GI(Protien) :
PubChem	None	uM		CTSS	-	GI(Protien) :
PubChem	Potency	uM	0.006	CBX1	-	GI(Protien) :
ChEMBL	Potency	nM	6.000	CBX1	-	Target : CHEMBL1741193

Download gene sets

gmt, text, Detailed text

Contact us
Tan Lab , Mail Stop 8117
12801 East 17th Avenue
Division of Medical Oncology , Department of Medicine
University of Colorado School of Medicine
Aurora, CO 80045, USA

* Best viewed in the latest version of Chrome (42+), Safari (8+), IE (11+) or Firefox (35+).