Tan Lab | DSigDB

Gene Set: D4 : TTD - 3-Bromo-7-Nitroindazole

Collection

D4 : TTD

Chemical Name

3-Bromo-7-Nitroindazole ( From PubChem : 3-BROMO-7-NITROINDAZOLE )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Not	Not	Not	Not	Not	Not	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
242.03 g/mol	1	1	2.7568	True

Structure

InChI

InChI=1S/C7H4BrN3O2/c8-7-4-2-1-3-5(11(12)13)6(4)9-10-7/h1-3H,(H,9,10)

InChIKey

NFSTZPMYAZRZPC-UHFFFAOYSA-N

Links

Gene (8 / 17)

⊖ Less

Source	Type	Unit	Value	Gene	PMID	Other
TTD	Inhibitor			NOS1		Clinical trial target
TTD	Inhibitor			NOS1		Clinical trial target
TTD	Inhibitor			NOS2		Successful target
TTD	Inhibitor			NOS2		Successful target
TTD	Inhibitor			NOS3		Clinical trial target
TTD	Inhibitor			NOS3		Clinical trial target
PubChem	Potency	uM	12.589	ALOX15	-	GI(Protien) :
PubChem	None	uM		CYP1A2	-	GI(Protien) :
PubChem	None	uM		CYP1A2	-	GI(Protien) :
PubChem	Potency	uM	12.589	CYP3A4	-	GI(Protien) :
PubChem	None	uM		CYP3A4	-	GI(Protien) :
PubChem	None	uM		MAPT	-	GI(Protien) :
PubChem	Potency	uM	31.623	TDP1	-	GI(Protien) :
ChEMBL	Potency	nM	12589.300	ALOX15	-	Target : CHEMBL2903
ChEMBL	AC50	nM	125.890	CYP1A2	-	Target : CHEMBL3356
ChEMBL	AC50	nM	12589.200	CYP3A4	-	Target : CHEMBL340
ChEMBL	Potency	nM	12589.300	CYP3A4	-	Target : CHEMBL340

Download gene sets

gmt, text, Detailed text

Contact us
Tan Lab , Mail Stop 8117
12801 East 17th Avenue
Division of Medical Oncology , Department of Medicine
University of Colorado School of Medicine
Aurora, CO 80045, USA

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