Tan Lab | DSigDB

Gene Set: D4 : TTD - DICLOFENAC SODIUM

Collection

D4 : TTD

Chemical Name

DICLOFENAC SODIUM ( From PubChem : DICLOFENAC SODIUM )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Approved	Not	Not	Approved	Not	Approved	Approved	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
318.13 g/mol	1	2	3.1024	True

Structure

InChI

InChI=1S/C14H11Cl2NO2.Na/c15-10-5-3-6-11(16)14(10)17-12-7-2-1-4-9(12)8-13(18)19;/h1-7,17H,8H2,(H,18,19);/q;+1/p-1

InChIKey

Links

Gene (8 / 20)

⊖ Less

Source	Type	Unit	Value	Gene	PMID	Other
TTD	Inhibitor			AKR1C3		Research target
PubChem	Ratio Potency (uM)	uM	33.360	AR	-	GI(Protien) :
PubChem	Potency	uM	1.585	CYP2C9	-	GI(Protien) :
PubChem	Potency	uM	7.943	CYP2C9	-	GI(Protien) :
PubChem	None	uM		CYP2C9	-	GI(Protien) :
PubChem	Potency	uM	10.000	CYP3A4	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	0.001	ESR1	-	GI(Protien) :
PubChem	Potency	uM	6.310	HIF1A	-	GI(Protien) :
PubChem	Potency	uM	25.119	HIF1A	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	3.889	PPARG	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	11.882	PPARG	-	GI(Protien) :
PubChem	None	uM		PPARG	-	GI(Protien) :
PubChem	None	uM		SLC5A7	-	GI(Protien) :
ChEMBL	AC50	nM	7943.280	CYP2C9	-	Target : CHEMBL3397
ChEMBL	AC50	nM	1584.890	CYP2C9	-	Target : CHEMBL3397
ChEMBL	Potency	nM	1584.900	CYP2C9	-	Target : CHEMBL3397
ChEMBL	Potency	nM	7943.300	CYP2C9	-	Target : CHEMBL3397
ChEMBL	Potency	nM	10000.000	CYP3A4	-	Target : CHEMBL340
ChEMBL	Potency	nM	25118.900	HIF1A	-	Target : CHEMBL4261
ChEMBL	Potency	nM	6309.600	HIF1A	-	Target : CHEMBL4261

Download gene sets