DSigDB Home
Search Gene
Collections
Browse Gene Sets
Download
Help

Gene Set: D4 : TTD - Dextromethorphan+quinidine

Collection D4 : TTD
Chemical Name Dextromethorphan+quinidine ( From PubChem : DEXTROMETHORPHAN HYDROBROMIDE MONOHYDRATE )
FDA NPC WHO Indian Australia China Traditional
Herbal		 Clinical
Trail
NotNotNotNotNotNotNotNot
Molecular
Weight		 Hydrogen Bond
Donor Count		 Hydrogen Bond
Acceptor Count		 cLogP Lipinski Rule
370.324 g/mol 2 3 4.2151 True
Structure
InChI InChI=1S/C18H25NO.BrH.H2O/c1-19-10-9-18-8-4-3-5-15(18)17(19)11-13-6-7-14(20-2)12-16(13)18;;/h6-7,12,15,17H,3-5,8-11H2,1-2H3;1H;1H2/t15?,17?,18-;;/m0../s1
InChIKey STTADZBLEUMJRG-SMHRUTPJSA-N
Links

Gene (5 / 10)


⊖ Less
Source Type Unit Value Gene PMID Assay Other
TTDMultitargetCYP19A1Successful target
TTDInhibitorCYP19A1Successful target
TTDDrug(s)CYP19A1Successful target
PubChem PotencyuM3.981CYP2D6-GI(Protien) :
PubChem NoneuMCYP2D6-GI(Protien) :
PubChem NoneuMMDM2-GI(Protien) :
PubChem NoneuMMDM4-GI(Protien) :
PubChem NoneuMPRMT1-GI(Protien) :
ChEMBLAC50nM3981.070CYP2D6
-Target : CHEMBL289
ChEMBLPotencynM3981.100CYP2D6
-Target : CHEMBL289
Download gene sets gmt, text, Detailed text
Contact us
Tan Lab , Mail Stop 8117
12801 East 17th Avenue
Division of Medical Oncology , Department of Medicine
University of Colorado School of Medicine
Aurora, CO 80045, USA

* Best viewed in the latest version of Chrome (42+), Safari (8+), IE (11+) or Firefox (35+).