Tan Lab | DSigDB

Gene Set: D4 : TTD - 6,7-Dichloro-1,4-dihydro-quinoxaline-2,3-dione

Collection

D4 : TTD

Chemical Name

6,7-Dichloro-1,4-dihydro-quinoxaline-2,3-dione ( From PubChem : DCQX )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Not	Not	Not	Not	Not	Not	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
231.036 g/mol	2	2	1.5232	True

Structure

InChI

InChI=1S/C8H4Cl2N2O2/c9-3-1-5-6(2-4(3)10)12-8(14)7(13)11-5/h1-2H,(H,11,13)(H,12,14)

InChIKey

AVBSIKMUAFYZAV-UHFFFAOYSA-N

Links

Gene (6 / 9)

⊖ Less

Source	Type	Unit	Value	Gene	PMID	Other
TTD	Inhibitor			GRIN1		Research target
PubChem	None	uM		CYP1A2	-	GI(Protien) :
PubChem	None	uM		CYP1A2	-	GI(Protien) :
PubChem	Potency	uM	7.943	GBA	-	GI(Protien) :
PubChem	Potency	uM	11.220	SMN2	-	GI(Protien) :
ChEMBL	AC50	nM	5011.870	CYP1A2	-	Target : CHEMBL3356
ChEMBL	Potency	nM	7943.300	GBA	-	Target : CHEMBL2179
ChEMBL	Potency	nM	25118.900	HSD17B10	-	Target : CHEMBL4159
ChEMBL	Potency	nM	11220.200	SMN1; SMN2	-	Target : CHEMBL1293232

Download gene sets

gmt, text, Detailed text

Contact us
Tan Lab , Mail Stop 8117
12801 East 17th Avenue
Division of Medical Oncology , Department of Medicine
University of Colorado School of Medicine
Aurora, CO 80045, USA

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