DSigDB Home
Search Gene
Collections
Browse Gene Sets
Download
Help

Gene Set: D4 : TTD - Dantrolene

Collection D4 : TTD
Chemical Name Dantrolene ( From PubChem : DANTROLENE )
FDA NPC WHO Indian Australia China Traditional
Herbal		 Clinical
Trail
ApprovedNotNotNotNotNotNotNot
Molecular
Weight		 Hydrogen Bond
Donor Count		 Hydrogen Bond
Acceptor Count		 cLogP Lipinski Rule
314.253 g/mol 1 6 2.5304 True
Structure
InChI InChI=1S/C14H10N4O5/c19-13-8-17(14(20)16-13)15-7-11-5-6-12(23-11)9-1-3-10(4-2-9)18(21)22/h1-7H,8H2,(H,16,19,20)/b15-7+
InChIKey OZOMQRBLCMDCEG-VIZOYTHASA-N
Links

Gene (9 / 15)


⊖ Less
Source Type Unit Value Gene PMID Assay Other
TTDAntagonistRYR1Successful target
TTDDrug(s)RYR1Successful target
TTDAntagonistRYR2Successful target
TTDDrug(s)RYR2Successful target
TTDAntagonistRYR3Successful target
TTDDrug(s)RYR3Successful target
PubChem PotencyuM10.000MAPT-GI(Protien) :
PubChem PotencyuM14.125MAPT-GI(Protien) :
ChEMBLInhibition-CYP1A2
-Target : CHEMBL3356
ChEMBLInhibition-CYP2C19
-Target : CHEMBL3622
ChEMBLInhibition-CYP2C9
-Target : CHEMBL3397
ChEMBLInhibition-CYP2D6
-Target : CHEMBL289
ChEMBLInhibition-CYP3A4
-Target : CHEMBL340
ChEMBLPotencynM10000.000MAPT
-Target : CHEMBL1293224
ChEMBLPotencynM14125.400MAPT
-Target : CHEMBL1293224
Download gene sets gmt, text, Detailed text
Contact us
Tan Lab , Mail Stop 8117
12801 East 17th Avenue
Division of Medical Oncology , Department of Medicine
University of Colorado School of Medicine
Aurora, CO 80045, USA

* Best viewed in the latest version of Chrome (42+), Safari (8+), IE (11+) or Firefox (35+).