Tan Lab | DSigDB

Gene Set: D4 : TTD - 5-hydroxy-alpha-methyltryptamine

Collection

D4 : TTD

Chemical Name

5-hydroxy-alpha-methyltryptamine ( From PubChem : 3-(2-AMINOPROPYL)-1H-INDOL-5-OL )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Not	Not	Not	Not	Not	Not	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
190.242 g/mol	3	2	2.4635	True

Structure

InChI

InChI=1S/C11H14N2O/c1-7(12)4-8-6-13-11-3-2-9(14)5-10(8)11/h2-3,5-7,13-14H,4,12H2,1H3/t7-/m1/s1

InChIKey

LYPCGXKCQDYTFV-SSDOTTSWSA-N

Links

Gene (9 / 16)

⊖ Less

Source	Type	Unit	Value	Gene	PMID	Other
TTD	Inhibitor			HTR2B		Successful target
TTD	Inhibitor			HTR2C		Successful target
PubChem	Potency	uM	9.528	ARSA	-	GI(Protien) :
PubChem	Potency	uM	0.794	GLS	-	GI(Protien) :
PubChem	None	uM		HTR1D		GI(Protien) :
PubChem	None	uM		HTR1E		GI(Protien) :
PubChem	None	uM		HTR1E		GI(Protien) :
PubChem	None	uM		HTR1F		GI(Protien) :
PubChem	None	uM		HTR2A		GI(Protien) :
PubChem	None	uM		HTR2B		GI(Protien) :
PubChem	None	uM		HTR2B		GI(Protien) :
PubChem	None	uM		HTR2B		GI(Protien) :
PubChem	None	uM		HTR2C		GI(Protien) :
PubChem	None	uM		HTR2C		GI(Protien) :
PubChem	None	uM		HTR4		GI(Protien) :
PubChem	None	uM		HTR4		GI(Protien) :

Download gene sets

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Contact us
Tan Lab , Mail Stop 8117
12801 East 17th Avenue
Division of Medical Oncology , Department of Medicine
University of Colorado School of Medicine
Aurora, CO 80045, USA

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