Tan Lab | DSigDB

Gene Set: D4 : TTD - Ciglitazone

Collection

D4 : TTD

Chemical Name

Ciglitazone ( From PubChem : CIGLITAZONE )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Not	Not	Not	Not	Not	Not	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
333.445 g/mol	1	5	4.2587	True

Structure

InChI

InChI=1S/C18H23NO3S/c1-18(9-3-2-4-10-18)12-22-14-7-5-13(6-8-14)11-15-16(20)19-17(21)23-15/h5-8,15H,2-4,9-12H2,1H3,(H,19,20,21)/t15-/m0/s1

InChIKey

Links

Gene (10 / 18)

⊖ Less

Source	Type	Unit	Value	Gene	PMID	Other
TTD	Agonist			PPARG		Successful target
PubChem	None	uM		CYP19A1	-	GI(Protien) :
PubChem	Potency	uM	25.119	KAT2A	-	GI(Protien) :
PubChem	Potency	uM	31.623	KAT2A	-	GI(Protien) :
PubChem	Ratio Potency (uM)	uM	29.847	NR1H4	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	44.668	NR1I2	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	1.900	PPARG	-	GI(Protien) :
PubChem	Ratio Potency (uM)	uM	2.051	PPARG	-	GI(Protien) :
PubChem	Potency	uM	8.414	TDP1	-	GI(Protien) :
PubChem	Potency	uM	19.953	USP1	-	GI(Protien) :
ChEMBL	Potency	nM	25118.900	KAT2A	-	Target : CHEMBL5501
ChEMBL	Potency	nM	31622.800	KAT2A	-	Target : CHEMBL5501
ChEMBL	Activity	-		PPARA	-	Target : CHEMBL239
ChEMBL	Activity	-		PPARD	-	Target : CHEMBL3979
ChEMBL	Activity	-		PPARG	-	Target : CHEMBL235
ChEMBL	Activity	-		PPARG	-	Target : CHEMBL235
ChEMBL	Activity	-		PPARG	-	Target : CHEMBL235
ChEMBL	Activity	-		STAT3	-	Target : CHEMBL4026

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