Tan Lab | DSigDB

Gene Set: D4 : TTD - Chlorphrifos oxon

Collection

D4 : TTD

Chemical Name

Chlorphrifos oxon ( From PubChem : CHLORPYRIFOS OXON )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Not	Not	Not	Not	Not	Not	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
334.521 g/mol	0	5	4.6017	True

Structure

InChI

InChI=1S/C9H11Cl3NO4P/c1-3-15-18(14,16-4-2)17-9-7(11)5-6(10)8(12)13-9/h5H,3-4H2,1-2H3

InChIKey

Links

Gene (11 / 18)

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Source	Type	Unit	Value	Gene	PMID	Other
TTD	Inhibitor			ACHE		Successful target
TTD	Inhibitor			CNR1		Successful target
TTD	Inhibitor			FAAH		Successful target
PubChem	Ratio Potency (uM)	uM	46.840	AR	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	27.140	CYP19A1	-	GI(Protien) :
PubChem	None	uM		CYP19A1	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	12.226	ESR1	-	GI(Protien) :
PubChem	Ratio Potency (uM)	uM	43.385	ESR1	-	GI(Protien) :
PubChem	ER Potency (uM)	uM	44.696	ESR1	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	48.262	ESR1	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	21.741	NR1H4	-	GI(Protien) :
PubChem	None	uM		NR1H4	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	27.371	NR3C1	-	GI(Protien) :
PubChem	None	uM		NR3C1	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	12.226	PPARD	-	GI(Protien) :
PubChem	None	uM		PPARD	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	1.372	PPARG	-	GI(Protien) :
PubChem	None	uM		VDR	-	GI(Protien) :

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