Tan Lab | DSigDB

Gene Set: D4 : TTD - Chlorprothixene

Collection

D4 : TTD

Chemical Name

Chlorprothixene ( From PubChem : CHLORPROTHIXENE )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Not	Not	Not	Not	Not	Not	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
315.86 g/mol	0	2	5.188	False(3/4)

Structure

InChI

InChI=1S/C18H18ClNS/c1-20(2)11-5-7-14-15-6-3-4-8-17(15)21-18-10-9-13(19)12-16(14)18/h3-4,6-10,12H,5,11H2,1-2H3/b14-7+

InChIKey

Links

Gene (12 / 23)

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Source	Type	Unit	Value	Gene	PMID	Other
TTD	Antagonist			DRD2		Successful target
TTD	Drug(s)			DRD2		Successful target
PubChem	None	uM		KCNH2	-	GI(Protien) :
PubChem	None	uM		CYP1A2	-	GI(Protien) :
PubChem	None	uM		CYP1A2	-	GI(Protien) :
PubChem	Potency	uM	2.512	CYP2D6	-	GI(Protien) :
PubChem	None	uM		CYP2D6	-	GI(Protien) :
PubChem	Potency	uM	23.715	TDP1	-	GI(Protien) :
PubChem	Potency	uM	23.715	TDP1	-	GI(Protien) :
PubChem	None	uM		CHRM1	-	GI(Protien) :
PubChem	None	uM		CHRM4	-	GI(Protien) :
PubChem	None	uM		CHRM5	-	GI(Protien) :
PubChem	None	uM		DRD1	-	GI(Protien) :
PubChem	None	uM		DRD2	-	GI(Protien) :
PubChem	None	uM		DRD3	-	GI(Protien) :
PubChem	None	uM		IL1B	-	GI(Protien) :
PubChem	None	uM		RGS4	-	GI(Protien) :
PubChem	None	uM		RGS4	-	GI(Protien) :
PubChem	Potency	uM	29.093	TDP1	-	GI(Protien) :
ChEMBL	AC50	nM	3981.070	CYP1A2	-	Target : CHEMBL3356
ChEMBL	AC50	nM	1584.890	CYP1A2	-	Target : CHEMBL3356
ChEMBL	AC50	nM	2511.890	CYP2D6	-	Target : CHEMBL289
ChEMBL	Potency	nM	2511.900	CYP2D6	-	Target : CHEMBL289

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