Tan Lab | DSigDB

Gene Set: D4 : TTD - 2-Methoxyestradiol

Collection

D4 : TTD

Chemical Name

2-Methoxyestradiol ( From PubChem : 2-METHOXYESTRADIOL )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Not	Not	Not	Not	Not	Not	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
302.408 g/mol	2	3	3.6178	True

Structure

InChI

InChI=1S/C19H26O3/c1-19-8-7-12-13(15(19)5-6-18(19)21)4-3-11-9-16(20)17(22-2)10-14(11)12/h9-10,12-13,15,18,20-21H,3-8H2,1-2H3/t12-,13+,15-,18-,19-/m0/s1

InChIKey

CQOQDQWUFQDJMK-SSTWWWIQSA-N

Links

Gene (10 / 19)

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Source	Type	Unit	Value	Gene	PMID	Other
TTD	Drug(s)			TUBB		Successful target
PubChem	None	uM		APP	-	GI(Protien) :
PubChem	None	uM		GFER	-	GI(Protien) :
PubChem	Potency	uM	11.220	GLP1R	-	GI(Protien) :
PubChem	Potency	uM	1.585	GLS	-	GI(Protien) :
PubChem	Potency	uM	3.264	GMNN	-	GI(Protien) :
PubChem	Potency	uM	4.761	GMNN	-	GI(Protien) :
PubChem	Potency	uM	6.725	GMNN	-	GI(Protien) :
PubChem	None	uM		JAK2	-	GI(Protien) :
PubChem	Potency	uM	9.200	NFE2L2	-	GI(Protien) :
PubChem	Potency	uM	1.000	TDP1	-	GI(Protien) :
PubChem	Potency	uM	1.122	TDP1	-	GI(Protien) :
PubChem	Potency	uM	1.836	TDP1	-	GI(Protien) :
PubChem	Potency	uM	4.611	TDP1	-	GI(Protien) :
ChEMBL	Potency	nM	39810.700	EHMT2	-	Target : CHEMBL6032
ChEMBL	Potency	nM	4610.900	GMNN	-	Target : CHEMBL1293278
ChEMBL	Potency	nM	6725.200	GMNN	-	Target : CHEMBL1293278
ChEMBL	Potency	nM	4761.100	GMNN	-	Target : CHEMBL1293278
ChEMBL	Potency	nM	9200.000	NFE2L2	-	Target : CHEMBL1075094

Download gene sets

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