Tan Lab | DSigDB

Gene Set: D4 : TTD - 2-methoxy-1,4-naphthoquinone

Collection

D4 : TTD

Chemical Name

2-methoxy-1,4-naphthoquinone ( From PubChem : 2-METHOXY-1,4-NAPHTHOQUINONE )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Not	Not	Not	Not	Not	Not	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
188.179 g/mol	0	3	1.5959	True

Structure

InChI

InChI=1S/C11H8O3/c1-14-10-6-9(12)7-4-2-3-5-8(7)11(10)13/h2-6H,1H3

InChIKey

Links

Gene (21 / 24)

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Source	Type	Unit	Value	Gene	PMID	Other
TTD	Inhibitor			IDO1		Successful target
PubChem	None	uM		APAF1	-	GI(Protien) :
PubChem	Potency	uM	18.349	ATAD5	-	GI(Protien) :
PubChem	None	uM		CFTR	-	GI(Protien) :
PubChem	None	uM		DRD3	-	GI(Protien) :
PubChem	Potency	uM	10.000	FEN1	-	GI(Protien) :
PubChem	Potency	uM	18.356	GMNN	-	GI(Protien) :
PubChem	None	uM		HCRTR1	-	GI(Protien) :
PubChem	Potency	uM	11.582	IDH1	-	GI(Protien) :
PubChem	None	uM		MDM2	-	GI(Protien) :
PubChem	None	uM		MDM4	-	GI(Protien) :
PubChem	None	uM		MITF	-	GI(Protien) :
PubChem	Potency	uM	23.109	NFE2L2	-	GI(Protien) :
PubChem	None	uM		PAFAH1B3	-	GI(Protien) :
PubChem	Potency	uM	14.125	POLI	-	GI(Protien) :
PubChem	None	uM		SENP6	-	GI(Protien) :
PubChem	None	uM		SENP8	-	GI(Protien) :
PubChem	Potency	uM	1.413	SMAD3	-	GI(Protien) :
PubChem	Potency	uM	3.663	TDP1	-	GI(Protien) :
PubChem	Potency	uM	4.109	TDP1	-	GI(Protien) :
PubChem	None	uM		TNFRSF10B	-	GI(Protien) :
PubChem	Potency	uM	12.589	USP1	-	GI(Protien) :
ChEMBL	Potency	nM	18348.900	ATAD5	-	Target : CHEMBL1741209
ChEMBL	Potency	nM	23109.300	NFE2L2	-	Target : CHEMBL1075094

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