Tan Lab | DSigDB

Gene Set: D4 : TTD - pyridine-2,4-dicarboxylic acid

Collection

D4 : TTD

Chemical Name

pyridine-2,4-dicarboxylic acid ( From PubChem : PYRIDINE-2,4-DICARBOXYLIC ACID )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Not	Not	Not	Not	Not	Not	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
167.119 g/mol	2	5	0.478	True

Structure

InChI

InChI=1S/C7H5NO4/c9-6(10)4-1-2-8-5(3-4)7(11)12/h1-3H,(H,9,10)(H,11,12)

InChIKey

MJIVRKPEXXHNJT-UHFFFAOYSA-N

Links

Gene (11 / 15)

⊖ Less

Source	Type	Unit	Value	Gene	PMID	Other
TTD	Inhibitor			EGLN2		Clinical trial target
PubChem	None	uM		ARNT	-	GI(Protien) :
PubChem	Potency	uM	6.310	BAZ2B	-	GI(Protien) :
PubChem	None	uM		GAPDH	-	GI(Protien) :
PubChem	None	uM		NR0B1	-	GI(Protien) :
PubChem	None	uM		SIX1	-	GI(Protien) :
PubChem	None	uM		TACC3	-	GI(Protien) :
ChEMBL	Potency	nM	6309.600	BAZ2B	-	Target : CHEMBL1741220
ChEMBL	Inhibition	-		EGLN1	-	Target : CHEMBL5697
ChEMBL	Potency	nM	794.300	KDM4A	-	Target : CHEMBL5896
ChEMBL	AC50	nM	5853.000	KDM4A	-	Target : CHEMBL5896
ChEMBL	AC50	nM	1571.000	KDM4C	-	Target : CHEMBL6175
ChEMBL	Potency	nM	2643.000	KDM4E	-	Target : CHEMBL1293226
ChEMBL	Potency	nM	1169.000	KDM4E	-	Target : CHEMBL1293226
ChEMBL	Potency	nM	177.800	KDM4E	-	Target : CHEMBL1293226

Download gene sets

gmt, text, Detailed text

Contact us
Tan Lab , Mail Stop 8117
12801 East 17th Avenue
Division of Medical Oncology , Department of Medicine
University of Colorado School of Medicine
Aurora, CO 80045, USA

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