Tan Lab | DSigDB

Gene Set: D4 : TTD - 2,3-dichloro-1,4-naphthoquinone

Collection

D4 : TTD

Chemical Name

2,3-dichloro-1,4-naphthoquinone ( From PubChem : 2,3-DICHLORO-1,4-NAPHTHOQUINONE )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Not	Not	Not	Not	Not	Not	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
227.044 g/mol	0	2	2.7548	True

Structure

InChI

InChI=1S/C10H4Cl2O2/c11-7-8(12)10(14)6-4-2-1-3-5(6)9(7)13/h1-4H

InChIKey

Links

Gene (9 / 21)

⊖ Less

Source	Type	Unit	Value	Gene	PMID	Other
TTD	Inhibitor			IDO1		Successful target
PubChem	AhR Potency (uM)	uM	3.184	AHR	-	GI(Protien) :
PubChem	AhR Potency (uM)	uM	6.372	AHR	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	10.871	AHR	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	17.282	AHR	-	GI(Protien) :
PubChem	Potency	uM	50.119	AHR	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	4.871	AR	-	GI(Protien) :
PubChem	AR Potency (uM)	uM	6.132	AR	-	GI(Protien) :
PubChem	AR Potency (uM)	uM	6.352	AR	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	7.696	AR	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	2.176	CYP19A1	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	3.857	CYP19A1	-	GI(Protien) :
PubChem	None	uM		CYP19A1	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	30.731	ESR1	-	GI(Protien) :
PubChem	ER Potency (uM)	uM	45.108	ESR1	-	GI(Protien) :
PubChem	ER Potency (uM)	uM	52.431	ESR1	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	54.483	ESR1	-	GI(Protien) :
PubChem	Ratio Potency (uM)	uM	42.003	HSPB1	-	GI(Protien) :
PubChem	Potency	uM	2.731	NFE2L2	-	GI(Protien) :
PubChem	None	uM		NR1H4	-	GI(Protien) :
PubChem	None	uM		PPME1	-	GI(Protien) :

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