Tan Lab | DSigDB

Gene Set: D4 : TTD - N-(2-morpholinophenyl)-5-nitrofuran-2-carboxamide

Collection

D4 : TTD

Chemical Name

N-(2-morpholinophenyl)-5-nitrofuran-2-carboxamide ( From PubChem : CHEMBL251369 )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Not	Not	Not	Not	Not	Not	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
317.297 g/mol	1	5	2.9379	True

Structure

InChI

InChI=1S/C15H15N3O5/c19-15(13-5-6-14(23-13)18(20)21)16-11-3-1-2-4-12(11)17-7-9-22-10-8-17/h1-6H,7-10H2,(H,16,19)

InChIKey

BIQWNNXDPVEAPZ-UHFFFAOYSA-N

Links

Gene (6 / 12)

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Source	Type	Unit	Value	Gene	PMID	Other
TTD	Inhibitor			CSF1R		Successful target
TTD	Inhibitor			CSF3R		Successful target
PubChem	None	uM		DRD2	-	GI(Protien) :
PubChem	AC50_uM	uM	3.635	HSP90AA1	-	GI(Protien) :
PubChem	AC50_uM	uM	11.933	MITF	-	GI(Protien) :
PubChem	AC50_uM	uM	11.933	MITF	-	GI(Protien) :
PubChem	AC50_uM	uM	11.933	MITF	-	GI(Protien) :
PubChem	Potency	uM	11.582	TDP1	-	GI(Protien) :
PubChem	Potency	uM	14.581	TDP1	-	GI(Protien) :
ChEMBL	AC50	nM	11933.000	MITF	-	Target : CHEMBL1741165
ChEMBL	AC50	nM	11933.000	MITF	-	Target : CHEMBL1741165
ChEMBL	AC50	nM	11933.000	MITF	-	Target : CHEMBL1741165

Download gene sets

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Contact us
Tan Lab , Mail Stop 8117
12801 East 17th Avenue
Division of Medical Oncology , Department of Medicine
University of Colorado School of Medicine
Aurora, CO 80045, USA

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