Tan Lab | DSigDB

Gene Set: D4 : TTD - R-N-PROPYLNORAPOMORPHINE

Collection

D4 : TTD

Chemical Name

R-N-PROPYLNORAPOMORPHINE ( From PubChem : CHEMBL225230 )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Not	Not	Not	Not	Not	Not	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
295.376 g/mol	2	3	3.568	True

Structure

InChI

InChI=1S/C19H21NO2/c1-2-9-20-10-8-12-4-3-5-14-17(12)15(20)11-13-6-7-16(21)19(22)18(13)14/h3-7,15,21-22H,2,8-11H2,1H3/t15-/m1/s1

InChIKey

Links

Gene (8 / 16)

⊖ Less

Source	Type	Unit	Value	Gene	PMID	Other
TTD	Inhibitor			DRD1		Successful target
PubChem	Potency	uM	35.481	ATXN2	-	GI(Protien) :
PubChem	Potency	uM	70.795	CBX1	-	GI(Protien) :
PubChem	Potency	uM	0.046	DRD1	-	GI(Protien) :
PubChem	Potency	uM	0.355	DRD1	-	GI(Protien) :
PubChem	Potency	uM	1.683	EHMT2	-	GI(Protien) :
PubChem	Potency	uM	1.413	GLS	-	GI(Protien) :
PubChem	None	uM		STK33	-	GI(Protien) :
PubChem	Potency	uM	7.943	VDR	-	GI(Protien) :
ChEMBL	Potency	nM	70794.600	CBX1	-	Target : CHEMBL1741193
ChEMBL	Potency	nM	354.800	DRD1	-	Target : CHEMBL2056
ChEMBL	Potency	nM	1683.400	EHMT2	-	Target : CHEMBL6032
ChEMBL	Potency	nM	1584.900	EHMT2	-	Target : CHEMBL6032
ChEMBL	Potency	nM	15848.900	MAPT	-	Target : CHEMBL1293224
ChEMBL	Potency	nM	28183.800	MAPT	-	Target : CHEMBL1293224
ChEMBL	Potency	nM	17782.800	MAPT	-	Target : CHEMBL1293224

Download gene sets