Tan Lab | DSigDB

Gene Set: D4 : TTD - 3-methoxy-N-(4-methylthiazol-2-yl)benzamide

Collection

D4 : TTD

Chemical Name

3-methoxy-N-(4-methylthiazol-2-yl)benzamide ( From PubChem : CHEMBL211740 )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Not	Not	Not	Not	Not	Not	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
248.301 g/mol	1	5	2.7854	True

Structure

InChI

InChI=1S/C12H12N2O2S/c1-8-7-17-12(13-8)14-11(15)9-4-3-5-10(6-9)16-2/h3-7H,1-2H3,(H,13,14,15)

InChIKey

PAGPVSQZNPBQLP-UHFFFAOYSA-N

Links

Gene (13 / 15)

⊖ Less

Source	Type	Unit	Value	Gene	PMID	Other
TTD	Inhibitor			ALOX5		Research target
PubChem	None	uM		APP	-	GI(Protien) :
PubChem	None	uM		CASP3	-	GI(Protien) :
PubChem	None	uM		NFKB1	-	GI(Protien) :
PubChem	Potency	uM	3.162	NPC1	-	GI(Protien) :
PubChem	Potency	uM	2.512	RAB9A	-	GI(Protien) :
PubChem	None	uM		RELA	-	GI(Protien) :
PubChem	None	uM		SENP6	-	GI(Protien) :
PubChem	None	uM		SENP7	-	GI(Protien) :
PubChem	None	uM		SENP8	-	GI(Protien) :
PubChem	Potency	uM	11.220	SMN2	-	GI(Protien) :
PubChem	None	uM		STAT1	-	GI(Protien) :
ChEMBL	Potency	nM	3162.300	NPC1	-	Target : CHEMBL1293277
ChEMBL	Potency	nM	2511.900	RAB9A	-	Target : CHEMBL1293294
ChEMBL	Potency	nM	11220.200	SMN1; SMN2	-	Target : CHEMBL1293232

Download gene sets

gmt, text, Detailed text

Contact us
Tan Lab , Mail Stop 8117
12801 East 17th Avenue
Division of Medical Oncology , Department of Medicine
University of Colorado School of Medicine
Aurora, CO 80045, USA

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