Tan Lab | DSigDB

Gene Set: D4 : TTD - N-(1H-benzo[d]imidazol-2-yl)-3-nitrobenzamide

Collection

D4 : TTD

Chemical Name

N-(1H-benzo[d]imidazol-2-yl)-3-nitrobenzamide ( From PubChem : CHEMBL210658 )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Not	Not	Not	Not	Not	Not	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
282.254 g/mol	2	3	3.3196	True

Structure

InChI

InChI=1S/C14H10N4O3/c19-13(9-4-3-5-10(8-9)18(20)21)17-14-15-11-6-1-2-7-12(11)16-14/h1-8H,(H2,15,16,17,19)

InChIKey

QPKROMNIEAEFQA-UHFFFAOYSA-N

Links

Gene (9 / 12)

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Source	Type	Unit	Value	Gene	PMID	Other
TTD	Inhibitor			IRAK4		Research target
PubChem	None	uM		AHR	-	GI(Protien) :
PubChem	Potency	uM	2.060	NFE2L2	-	GI(Protien) :
PubChem	Potency	uM	3.548	NPC1	-	GI(Protien) :
PubChem	Potency	uM	1.413	RAB9A	-	GI(Protien) :
PubChem	Potency	uM	11.220	SMN2	-	GI(Protien) :
PubChem	None	uM		STAT1	-	GI(Protien) :
PubChem	None	uM		STAT1	-	GI(Protien) :
PubChem	None	uM		STAT3	-	GI(Protien) :
ChEMBL	Potency	nM	3548.100	NPC1	-	Target : CHEMBL1293277
ChEMBL	Potency	nM	1412.500	RAB9A	-	Target : CHEMBL1293294
ChEMBL	Potency	nM	11220.200	SMN1; SMN2	-	Target : CHEMBL1293232

Download gene sets

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Contact us
Tan Lab , Mail Stop 8117
12801 East 17th Avenue
Division of Medical Oncology , Department of Medicine
University of Colorado School of Medicine
Aurora, CO 80045, USA

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