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Gene Set: D4 : TTD - 10-hydroxycamptothecin

Collection D4 : TTD
Chemical Name 10-hydroxycamptothecin ( From PubChem : 10-HYDROXYCAMPTOTHECIN )
FDA NPC WHO Indian Australia China Traditional
Herbal		 Clinical
Trail
NotNotNotNotNotNotApprovedNot
Molecular
Weight		 Hydrogen Bond
Donor Count		 Hydrogen Bond
Acceptor Count		 cLogP Lipinski Rule
364.351 g/mol 2 7 1.7852 True
Structure
InChI InChI=1S/C20H16N2O5/c1-2-20(26)14-7-16-17-11(5-10-6-12(23)3-4-15(10)21-17)8-22(16)18(24)13(14)9-27-19(20)25/h3-7,23,26H,2,8-9H2,1H3/t20-/m0/s1
InChIKey HAWSQZCWOQZXHI-FQEVSTJZSA-N
Links

Gene (4 / 11)


⊖ Less
Source Type Unit Value Gene PMID Assay Other
TTDInhibitorTOP1Successful target
PubChem PotencyuM12.589CYP3A4-GI(Protien) :
PubChem PotencyuM12.589HBB-GI(Protien) :
PubChem PotencyuM0.018TDP1-GI(Protien) :
PubChem PotencyuM0.021TDP1-GI(Protien) :
PubChem PotencyuM0.052TDP1-GI(Protien) :
PubChem PotencyuM0.058TDP1-GI(Protien) :
ChEMBLPotencynM12589.300CYP3A4
-Target : CHEMBL340
ChEMBLPotencynM12589.300HBB
-Target : CHEMBL4331
ChEMBLInhibition-TOP1
-Target : CHEMBL1781
ChEMBLInhibition-TOP1
-Target : CHEMBL1781
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