Tan Lab | DSigDB

Gene Set: D4 : TTD - S-(2,4-Dichlorobenzyl)isothiourea hydrobromide

Collection

D4 : TTD

Chemical Name

S-(2,4-Dichlorobenzyl)isothiourea hydrobromide ( From PubChem : CHEMBL1224483 )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Not	Not	Not	Not	Not	Not	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
316.045 g/mol	3	3	4.8782	True

Structure

InChI

InChI=1S/C8H8Cl2N2S.BrH/c9-6-2-1-5(7(10)3-6)4-13-8(11)12;/h1-3H,4H2,(H3,11,12);1H

InChIKey

Links

Gene (13 / 18)

⊖ Less

Source	Type	Unit	Value	Gene	PMID	Other
TTD	Inhibitor			IDO1		Successful target
PubChem	None	uM		ABCC1	-	GI(Protien) :
PubChem	Potency	uM	10.322	ATAD5	-	GI(Protien) :
PubChem	None	uM		DRD1	-	GI(Protien) :
PubChem	None	uM		GFER	-	GI(Protien) :
PubChem	Potency	uM	7.080	GLP1R	-	GI(Protien) :
PubChem	None	uM		GNA15	-	GI(Protien) :
PubChem	None	uM		IL1B	-	GI(Protien) :
PubChem	None	uM		MRGPRX1	-	GI(Protien) :
PubChem	None	uM		MRGPRX1	-	GI(Protien) :
PubChem	None	uM		PLA2G3	-	GI(Protien) :
PubChem	None	uM		PPP1CA	-	GI(Protien) :
PubChem	None	uM		TAAR1	-	GI(Protien) :
PubChem	None	uM		TAAR1	-	GI(Protien) :
PubChem	None	uM		TAAR1	-	GI(Protien) :
PubChem	Potency	uM	18.356	TDP1	-	GI(Protien) :
PubChem	Potency	uM	23.109	TDP1	-	GI(Protien) :
ChEMBL	Potency	nM	10322.500	ATAD5	-	Target : CHEMBL1741209

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