Tan Lab | DSigDB

Gene Set: D4 : TTD - Benzyl-(2-thiophen-2-yl-quinazolin-4-yl)-amine

Collection

D4 : TTD

Chemical Name

Benzyl-(2-thiophen-2-yl-quinazolin-4-yl)-amine ( From PubChem : CHEMBL117108 )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Not	Not	Not	Not	Not	Not	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
317.408 g/mol	1	4	5.0434	False(3/4)

Structure

InChI

InChI=1S/C19H15N3S/c1-2-7-14(8-3-1)13-20-18-15-9-4-5-10-16(15)21-19(22-18)17-11-6-12-23-17/h1-12H,13H2,(H,20,21,22)

InChIKey

XITKIGBKTNSGCP-UHFFFAOYSA-N

Links

Gene (4 / 11)

⊖ Less

Source	Type	Unit	Value	Gene	PMID	Other
TTD	Inhibitor			PDE4A		Successful target
TTD	Inhibitor			PDE4B		Research target
PubChem	None	uM		FGF22	-	GI(Protien) :
PubChem	Potency	uM	0.501	GBA	-	GI(Protien) :
PubChem	Potency	uM	5.661	GBA	-	GI(Protien) :
PubChem	Potency	uM	7.127	GBA	-	GI(Protien) :
PubChem	Potency	uM	7.127	GBA	-	GI(Protien) :
ChEMBL	Potency	nM	501.200	GBA	-	Target : CHEMBL2179
ChEMBL	Potency	nM	7127.100	GBA	-	Target : CHEMBL2179
ChEMBL	Potency	nM	7127.100	GBA	-	Target : CHEMBL2179
ChEMBL	Potency	nM	5661.300	GBA	-	Target : CHEMBL2179

Download gene sets

gmt, text, Detailed text

Contact us
Tan Lab , Mail Stop 8117
12801 East 17th Avenue
Division of Medical Oncology , Department of Medicine
University of Colorado School of Medicine
Aurora, CO 80045, USA

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