Tan Lab | DSigDB

Gene Set: D4 : TTD - 4-[(3,5-diamino-1H-pyrazol-4-yl)diazenyl]phenol

Collection

D4 : TTD

Chemical Name

4-[(3,5-diamino-1H-pyrazol-4-yl)diazenyl]phenol ( From PubChem : CDK9 INHIBITOR II )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Not	Not	Not	Not	Not	Not	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
218.215 g/mol	4	6	1.2725	True

Structure

InChI

InChI=1S/C9H10N6O/c10-8-7(9(11)15-14-8)13-12-5-1-3-6(16)4-2-5/h1-4,13H,(H5,10,11,14,15)

InChIKey

Links

Gene (21 / 23)

⊖ Less

Source	Type	Unit	Gene	PMID	Other
TTD	Inhibitor		ABL1		Successful target
TTD	Inhibitor		ABL2		Successful target
TTD	Inhibitor		AKT1		Clinical trial target
TTD	Inhibitor		AKT2		Clinical trial target
TTD	Inhibitor		AKT3		Clinical trial target
TTD	Inhibitor		CCNA2		Research target
TTD	Inhibitor		CCND1		Clinical trial target
TTD	Inhibitor		CCNE1		Research target
TTD	Inhibitor		CDK2		Clinical trial target
TTD	Inhibitor		CDK4		Clinical trial target
TTD	Inhibitor		CDK9		Clinical trial target
TTD	Inhibitor		CHEK1		Clinical trial target
TTD	Inhibitor		CSNK2A1		Clinical trial target
TTD	Inhibitor		CSNK2A1		Clinical trial target
TTD	Inhibitor		GSK3B		Clinical trial target
TTD	Inhibitor		MAPK1		Research target
TTD	Inhibitor		MAPK14		Clinical trial target
TTD	Inhibitor		PCNA		Research target
TTD	Inhibitor		PRKACA		Research target
TTD	Inhibitor		PRKAR2B		Research target
TTD	Inhibitor		RPS6KB1		Discontinued target
ChEMBL	Inhibition	-	CDK7	-	Target : CHEMBL3055
ChEMBL	Inhibition	-	CDK7	-	Target : CHEMBL3055

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