Tan Lab | DSigDB

Gene Set: D4 : TTD - CAPSAZEPINE

Collection

D4 : TTD

Chemical Name

CAPSAZEPINE ( From PubChem : CAPSAZEPINE )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Not	Not	Not	Not	Not	Not	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
376.9 g/mol	3	5	3.9454	True

Structure

InChI

InChI=1S/C19H21ClN2O2S/c20-16-5-3-13(4-6-16)7-8-21-19(25)22-9-1-2-14-10-17(23)18(24)11-15(14)12-22/h3-6,10-11,23-24H,1-2,7-9,12H2,(H,21,25)

InChIKey

DRCMAZOSEIMCHM-UHFFFAOYSA-N

Links

Gene (29 / 70)

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Source	Type	Unit	Value	Gene	PMID	Other
TTD	Inhibitor			TRPV1		Clinical trial target
TTD	Inhibitor			TRPV4		Research target
PubChem	Potency	uM	15.849	ALDH1A1	-	GI(Protien) :
PubChem	Potency	uM	19.953	ALDH1A1	-	GI(Protien) :
PubChem	Potency	uM	44.668	BAZ2B	-	GI(Protien) :
PubChem	Potency	uM	44.668	CBX1	-	GI(Protien) :
PubChem	Potency	uM	50.119	CBX1	-	GI(Protien) :
PubChem	None	uM		CYP1A2	-	GI(Protien) :
PubChem	None	uM		CYP1A2	-	GI(Protien) :
PubChem	Potency	uM	0.316	CYP2C19	-	GI(Protien) :
PubChem	Potency	uM	5.012	CYP2C19	-	GI(Protien) :
PubChem	None	uM		CYP2C19	-	GI(Protien) :
PubChem	Potency	uM	3.981	CYP2C9	-	GI(Protien) :
PubChem	Potency	uM	10.000	CYP2C9	-	GI(Protien) :
PubChem	None	uM		CYP2C9	-	GI(Protien) :
PubChem	Potency	uM	12.589	CYP2D6	-	GI(Protien) :
PubChem	None	uM		CYP2D6	-	GI(Protien) :
PubChem	Potency	uM	3.162	CYP3A4	-	GI(Protien) :
PubChem	None	uM		CYP3A4	-	GI(Protien) :
PubChem	Potency	uM	1.995	DRD1	-	GI(Protien) :
PubChem	None	uM		DRD1	-	GI(Protien) :
PubChem	Potency	uM	1.995	EHMT2	-	GI(Protien) :
PubChem	Potency	uM	3.548	EHMT2	-	GI(Protien) :
PubChem	Potency	uM	4.744	EHMT2	-	GI(Protien) :
PubChem	None	uM		GFER	-	GI(Protien) :
PubChem	Potency	uM	2.239	GLS	-	GI(Protien) :
PubChem	Potency	uM	3.548	GMNN	-	GI(Protien) :
PubChem	Potency	uM	14.125	HPGD	-	GI(Protien) :
PubChem	None	uM		HSP90AA1	-	GI(Protien) :
PubChem	Potency	uM	31.623	IDH1	-	GI(Protien) :
PubChem	None	uM		IL1B	-	GI(Protien) :
PubChem	Potency	uM	39.811	MPHOSPH8	-	GI(Protien) :
PubChem	None	uM		PAFAH1B2	-	GI(Protien) :
PubChem	None	uM		PAFAH1B2	-	GI(Protien) :
PubChem	Potency	uM	16.834	RGS4	-	GI(Protien) :
PubChem	None	uM		STK33	-	GI(Protien) :
PubChem	Potency	uM	7.080	TDP1	-	GI(Protien) :
PubChem	Potency	uM	8.912	TDP1	-	GI(Protien) :
PubChem	Potency	uM	13.336	TDP1	-	GI(Protien) :
ChEMBL	Potency	nM	19952.600	ALDH1A1	-	Target : CHEMBL3577
ChEMBL	Potency	nM	15848.900	ALDH1A1	-	Target : CHEMBL3577
ChEMBL	Potency	nM	12589.300	ALOX15B	-	Target : CHEMBL2457
ChEMBL	Potency	nM	44668.400	BAZ2B	-	Target : CHEMBL1741220
ChEMBL	Potency	nM	44668.400	CBX1	-	Target : CHEMBL1741193
ChEMBL	AC50	nM	19952.600	CYP1A2	-	Target : CHEMBL3356
ChEMBL	AC50	nM	316.230	CYP2C19	-	Target : CHEMBL3622
ChEMBL	Potency	nM	5011.900	CYP2C19	-	Target : CHEMBL3622
ChEMBL	Potency	nM	316.200	CYP2C19	-	Target : CHEMBL3622
ChEMBL	AC50	nM	3981.070	CYP2C9	-	Target : CHEMBL3397
ChEMBL	Potency	nM	3981.100	CYP2C9	-	Target : CHEMBL3397
ChEMBL	Potency	nM	10000.000	CYP2C9	-	Target : CHEMBL3397
ChEMBL	AC50	nM	12589.200	CYP2D6	-	Target : CHEMBL289
ChEMBL	Potency	nM	12589.300	CYP2D6	-	Target : CHEMBL289
ChEMBL	AC50	nM	3162.280	CYP3A4	-	Target : CHEMBL340
ChEMBL	Potency	nM	3162.300	CYP3A4	-	Target : CHEMBL340
ChEMBL	Potency	nM	1995.300	DRD1	-	Target : CHEMBL2056
ChEMBL	Potency	nM	3548.100	EHMT2	-	Target : CHEMBL6032
ChEMBL	Potency	nM	4744.400	EHMT2	-	Target : CHEMBL6032
ChEMBL	Potency	nM	1995.300	EHMT2	-	Target : CHEMBL6032
ChEMBL	Potency	nM	3548.100	GMNN	-	Target : CHEMBL1293278
ChEMBL	Potency	nM	14125.400	HPGD	-	Target : CHEMBL1293255
ChEMBL	Potency	nM	15848.900	HSD17B10	-	Target : CHEMBL4159
ChEMBL	Potency	nM	1584.900	HSD17B10	-	Target : CHEMBL4159
ChEMBL	Potency	nM	631.000	HSD17B10	-	Target : CHEMBL4159
ChEMBL	Potency	nM	44668.400	KDM4A	-	Target : CHEMBL5896
ChEMBL	Potency	nM	28183.800	KDM4E	-	Target : CHEMBL1293226
ChEMBL	Potency	nM	10000.000	MAPT	-	Target : CHEMBL1293224
ChEMBL	Potency	nM	39810.700	MPHOSPH8	-	Target : CHEMBL1741210
ChEMBL	Inhibition	-		TRPV1	-	Target : CHEMBL4794
ChEMBL	Inhibition	-		TRPV1	-	Target : CHEMBL4794

Download gene sets

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