Tan Lab | DSigDB

Gene Set: D4 : TTD - Caffeic acid

Collection

D4 : TTD

Chemical Name

Caffeic acid ( From PubChem : CAFFEIC ACID )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Not	Not	Not	Not	Not	Not	Approved	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
180.157 g/mol	3	4	1.1956	True

Structure

InChI

InChI=1S/C9H8O4/c10-7-3-1-6(5-8(7)11)2-4-9(12)13/h1-5,10-11H,(H,12,13)/b4-2+

InChIKey

Links

Gene (14 / 21)

⊖ Less

Source	Type	Unit	Value	Gene	PMID	Other
TTD	Inhibitor			ALOX5		Successful target
TTD	Inhibitor			MIF		Clinical trial target
PubChem	None	uM		ALPL	-	GI(Protien) :
PubChem	Potency	uM	3.162	EHMT2	-	GI(Protien) :
PubChem	Potency	uM	10.621	EHMT2	-	GI(Protien) :
PubChem	Potency	uM	11.220	EHMT2	-	GI(Protien) :
PubChem	None	uM		ESR2	-	GI(Protien) :
PubChem	Potency	uM	7.943	GAA	-	GI(Protien) :
PubChem	None	uM		GAPDH	-	GI(Protien) :
PubChem	None	uM		GFER	-	GI(Protien) :
PubChem	Potency	uM	1.995	GLS	-	GI(Protien) :
PubChem	None	uM		HSP90AA1	-	GI(Protien) :
PubChem	None	uM		MCL1	-	GI(Protien) :
PubChem	IC50	uM		MPI	-	GI(Protien) :
ChEMBL	Potency	nM	3162.300	EHMT2	-	Target : CHEMBL6032
ChEMBL	Potency	nM	11220.200	EHMT2	-	Target : CHEMBL6032
ChEMBL	Potency	nM	10621.300	EHMT2	-	Target : CHEMBL6032
ChEMBL	Potency	nM	7943.300	GAA	-	Target : CHEMBL2608
ChEMBL	Potency	nM	1995.300	HSD17B10	-	Target : CHEMBL4159
ChEMBL	Potency	nM	15848.900	KDM4E	-	Target : CHEMBL1293226
ChEMBL	Potency	nM	562.300	KDM4E	-	Target : CHEMBL1293226

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