DSigDB Home
Search Gene
Collections
Browse Gene Sets
Download
Help

Gene Set: D4 : TTD - Buspirone

Collection D4 : TTD
Chemical Name Buspirone ( From PubChem : BUSPIRONE )
FDA NPC WHO Indian Australia China Traditional
Herbal		 Clinical
Trail
ApprovedNotNotApprovedNotNotNotNot
Molecular
Weight		 Hydrogen Bond
Donor Count		 Hydrogen Bond
Acceptor Count		 cLogP Lipinski Rule
385.503 g/mol 0 7 2.029 True
Structure
InChI InChI=1S/C21H31N5O2/c27-18-16-21(6-1-2-7-21)17-19(28)26(18)11-4-3-10-24-12-14-25(15-13-24)20-22-8-5-9-23-20/h5,8-9H,1-4,6-7,10-17H2
InChIKey QWCRAEMEVRGPNT-UHFFFAOYSA-N
Links

Gene (5 / 13)


⊖ Less
Source Type Unit Value Gene PMID Assay Other
TTDAgonistHTR1ASuccessful target
TTDDrug(s)HTR1ASuccessful target
PubChem PotencyuM4.467ALDH1A1-GI(Protien) :
PubChem PotencyuM12.589EHMT2-GI(Protien) :
PubChem Potency-Replicate_1uM30.638ESR1-GI(Protien) :
PubChem ER Potency (uM)uM38.571ESR1-GI(Protien) :
PubChem NoneuMHTR1AGI(Protien) :
PubChem NoneuMHTR1AGI(Protien) :
PubChem NoneuMHTR1AGI(Protien) :
PubChem Potency-Replicate_1uM27.306NFE2L2-GI(Protien) :
PubChem Ratio Potency (uM)uM30.638NFE2L2-GI(Protien) :
ChEMBLPotencynM4466.800ALDH1A1
-Target : CHEMBL3577
ChEMBLPotencynM12589.300EHMT2
-Target : CHEMBL6032
Download gene sets gmt, text, Detailed text
Contact us
Tan Lab , Mail Stop 8117
12801 East 17th Avenue
Division of Medical Oncology , Department of Medicine
University of Colorado School of Medicine
Aurora, CO 80045, USA

* Best viewed in the latest version of Chrome (42+), Safari (8+), IE (11+) or Firefox (35+).