Tan Lab | DSigDB

Gene Set: D4 : TTD - Bromocriptine

Collection

D4 : TTD

Chemical Name

Bromocriptine ( From PubChem : BROMOCRIPTINE )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Approved	Not	Not	Approved	Not	Approved	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
654.594 g/mol	3	9	3.3974	False(3/4)

Structure

InChI

InChI=1S/C32H40BrN5O5/c1-16(2)12-24-29(40)37-11-7-10-25(37)32(42)38(24)30(41)31(43-32,17(3)4)35-28(39)18-13-20-19-8-6-9-22-26(19)21(27(33)34-22)14-23(20)36(5)15-18/h6,8-9,13,16-18,23-25,34,42H,7,10-12,14-15H2,1-5H3,(H,35,39)/t18-,23-,24+,25+,31-,32+/m1/s1

InChIKey

OZVBMTJYIDMWIL-AYFBDAFISA-N

Links

Gene (17 / 26)

⊖ Less

Source	Type	Unit	Value	Gene	PMID	Other
TTD	Agonist			DRD2		Successful target
TTD	Drug(s)			DRD2		Successful target
PubChem	Potency-Replicate_1	uM	21.314	AR	-	GI(Protien) :
PubChem	Ratio Potency (uM)	uM	22.148	AR	-	GI(Protien) :
PubChem	AR Potency (uM)	uM	25.115	AR	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	26.603	AR	-	GI(Protien) :
PubChem	Potency	uM	3.264	DRD1	-	GI(Protien) :
PubChem	None	uM		DRD3	-	GI(Protien) :
PubChem	None	uM		DRD3	-	GI(Protien) :
PubChem	Potency	uM	23.778	EHMT2	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	9.521	ESR1	-	GI(Protien) :
PubChem	Ratio Potency (uM)	uM	17.593	ESR1	-	GI(Protien) :
PubChem	None	uM		HTR1A		GI(Protien) :
PubChem	None	uM		HTR1B		GI(Protien) :
PubChem	None	uM		HTR1D		GI(Protien) :
PubChem	None	uM		HTR2A		GI(Protien) :
PubChem	None	uM		HTR2B		GI(Protien) :
PubChem	None	uM		HTR2C		GI(Protien) :
PubChem	None	uM		HTR6		GI(Protien) :
PubChem	None	uM		NR3C1	-	GI(Protien) :
PubChem	None	uM		STK33	-	GI(Protien) :
PubChem	Potency	uM	9.441	TDP1	-	GI(Protien) :
PubChem	Potency	uM	21.136	TDP1	-	GI(Protien) :
PubChem	Potency	uM	28.184	VDR	-	GI(Protien) :
ChEMBL	Potency	nM	23778.100	EHMT2	-	Target : CHEMBL6032
ChEMBL	Potency	nM	14125.400	EHMT2	-	Target : CHEMBL6032

Download gene sets

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