Gene Set: D4 : TTD - BMS-540215
| Collection |
D4 : TTD |
| Chemical Name |
BMS-540215 ( From PubChem : B R I V A N I B ) |
| FDA |
NPC |
WHO |
Indian |
Australia |
China |
Traditional
Herbal |
Clinical
Trail |
| Not | Not | Not | Not | Not | Not | Not | Not |
|
Molecular
Weight |
Hydrogen Bond
Donor Count |
Hydrogen Bond
Acceptor Count |
cLogP |
Lipinski Rule |
| 370.378 g/mol |
2 |
6 |
3.5184 |
True |
|
| Structure |
|
| InChI |
I n C h I = 1 S / C 1 9 H 1 9 F N 4 O 3 / c 1 - 1 0 - 6 - 1 3 - 1 4 ( 2 3 - 1 0 ) 4 - 5 - 1 5 ( 1 7 ( 1 3 ) 2 0 ) 2 7 - 1 9 - 1 8 - 1 2 ( 3 ) 1 6 ( 2 6 - 8 - 1 1 ( 2 ) 2 5 ) 7 - 2 4 ( 1 8 ) 2 2 - 9 - 2 1 - 1 9 / h 4 - 7 , 9 , 1 1 , 2 3 , 2 5 H , 8 H 2 , 1 - 3 H 3 / t 1 1 - / m 1 / s 1 |
| InChIKey |
W C W U X E G Q K L T G D X - L L V K D O N J S A - N
|
| Links |
|
Gene
(6 /
8)
⊖ Less
|
| Source | Type | Unit | Value | Gene | PMID | Assay | Other | | TTD | Inhibitor | CYP3A4 | | | Successful target | | TTD | Inhibitor | FGFR1 | | | Clinical trial target | | TTD | Drug(s) | FGFR1 | | | Clinical trial target | | TTD | Inhibitor | FLT1 | | | Clinical trial target | | TTD | Drug(s) | FLT1 | | | Successful target | | TTD | Inhibitor | KCNH2 | | | Successful target | | TTD | Inhibitor | KDR | | | Successful target | | PubChem | Potency | uM | 1.729 | YES1 |  | | GI(Protien) : |
|
| Download gene sets |
gmt, text, Detailed text
|
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University of Colorado School of Medicine
Aurora, CO 80045, USA
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