Gene Set: D4 : TTD - Bosutinib
| Collection |
D4 : TTD |
| Chemical Name |
Bosutinib ( From PubChem : B O S U T I N I B ) |
| FDA |
NPC |
WHO |
Indian |
Australia |
China |
Traditional
Herbal |
Clinical
Trail |
| Approved | Not | Not | Not | Not | Not | Not | Not |
|
Molecular
Weight |
Hydrogen Bond
Donor Count |
Hydrogen Bond
Acceptor Count |
cLogP |
Lipinski Rule |
| 530.446 g/mol |
1 |
7 |
5.13918 |
False(2/4) |
|
| Structure |
|
| InChI |
I n C h I = 1 S / C 2 6 H 2 9 C l 2 N 5 O 3 / c 1 - 3 2 - 6 - 8 - 3 3 ( 9 - 7 - 3 2 ) 5 - 4 - 1 0 - 3 6 - 2 5 - 1 3 - 2 1 - 1 8 ( 1 1 - 2 4 ( 2 5 ) 3 5 - 3 ) 2 6 ( 1 7 ( 1 5 - 2 9 ) 1 6 - 3 0 - 2 1 ) 3 1 - 2 2 - 1 4 - 2 3 ( 3 4 - 2 ) 2 0 ( 2 8 ) 1 2 - 1 9 ( 2 2 ) 2 7 / h 1 1 - 1 4 , 1 6 H , 4 - 1 0 H 2 , 1 - 3 H 3 , ( H , 3 0 , 3 1 ) |
| InChIKey |
U B P Y I L G K F Z Z V D X - U H F F F A O Y S A - N
|
| Links |
|
Gene
(4 /
10)
⊖ Less
|
| Source | Type | Unit | Value | Gene | PMID | Assay | Other | | TTD | Multitarget | ABL1 | | | Successful target | | TTD | Inhibitor | ABL1 | | | Successful target | | TTD | Drug(s) | ABL1 | | | Successful target | | TTD | Multitarget | ABL2 | | | Successful target | | TTD | Inhibitor | ABL2 | | | Successful target | | TTD | Drug(s) | ABL2 | | | Successful target | | TTD | Multitarget | SRC | | | Successful target | | TTD | Inhibitor | SRC | | | Successful target | | TTD | Drug(s) | SRC | | | Successful target | | PubChem | None | uM | | SLK | - | | GI(Protien) : |
|
| Download gene sets |
gmt, text, Detailed text
|
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