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Gene Set: D4 : TTD - Bosentan

Collection D4 : TTD
Chemical Name Bosentan ( From PubChem : BOSENTAN )
FDA NPC WHO Indian Australia China Traditional
Herbal		 Clinical
Trail
ApprovedNotNotApprovedNotNotNotNot
Molecular
Weight		 Hydrogen Bond
Donor Count		 Hydrogen Bond
Acceptor Count		 cLogP Lipinski Rule
551.614 g/mol 2 11 5.3577 False(1/4)
Structure
InChI InChI=1S/C27H29N5O6S/c1-27(2,3)18-10-12-19(13-11-18)39(34,35)32-23-22(38-21-9-6-5-8-20(21)36-4)26(37-17-16-33)31-25(30-23)24-28-14-7-15-29-24/h5-15,33H,16-17H2,1-4H3,(H,30,31,32)
InChIKey GJPICJJJRGTNOD-UHFFFAOYSA-N
Links

Gene (2 / 6)


⊖ Less
Source Type Unit Value Gene PMID Assay Other
TTDAntagonistEDNRASuccessful target
TTDMultitargetEDNRASuccessful target
TTDDrug(s)EDNRASuccessful target
TTDAntagonistEDNRBSuccessful target
TTDMultitargetEDNRBSuccessful target
TTDDrug(s)EDNRBSuccessful target
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