Gene Set: D4 : TTD - BMS-536924
| Collection |
D4 : TTD |
| Chemical Name |
BMS-536924 ( From PubChem : B M S - 5 3 6 9 2 4 ) |
| FDA |
NPC |
WHO |
Indian |
Australia |
China |
Traditional
Herbal |
Clinical
Trail |
| Not | Not | Not | Not | Not | Not | Not | Not |
|
Molecular
Weight |
Hydrogen Bond
Donor Count |
Hydrogen Bond
Acceptor Count |
cLogP |
Lipinski Rule |
| 479.959 g/mol |
4 |
6 |
2.4358 |
True |
|
| Structure |
|
| InChI |
I n C h I = 1 S / C 2 5 H 2 6 C l N 5 O 3 / c 1 - 1 5 - 1 1 - 1 8 ( 3 1 - 7 - 9 - 3 4 - 1 0 - 8 - 3 1 ) 1 3 - 2 0 - 2 3 ( 1 5 ) 3 0 - 2 4 ( 2 9 - 2 0 ) 2 2 - 1 9 ( 5 - 6 - 2 7 - 2 5 ( 2 2 ) 3 3 ) 2 8 - 1 4 - 2 1 ( 3 2 ) 1 6 - 3 - 2 - 4 - 1 7 ( 2 6 ) 1 2 - 1 6 / h 2 - 6 , 1 1 - 1 3 , 2 1 , 2 8 - 3 0 , 3 2 H , 7 - 1 0 , 1 4 H 2 , 1 H 3 / b 2 4 - 2 2 + / t 2 1 - / m 1 / s 1 |
| InChIKey |
U G Q M U R P I M Y A L P H - P Z J Q A W Q V S A - N
|
| Links |
|
Gene
(14 /
14)
⊖ Less
|
| Source | Type | Unit | Value | Gene | PMID | Assay | Other | | TTD | Inhibitor | AKT1 | | | Clinical trial target | | TTD | Inhibitor | AKT2 | | | Clinical trial target | | TTD | Inhibitor | AKT3 | | | Clinical trial target | | TTD | Inhibitor | CCNE1 | | | Research target | | TTD | Inhibitor | CDK2 | | | Clinical trial target | | TTD | Inhibitor | CYP3A4 | | | Successful target | | TTD | Inhibitor | ERBB2 | | | Research target | | TTD | Inhibitor | IGF1R | | | Successful target | | TTD | Inhibitor | KDR | | | Successful target | | TTD | Inhibitor | LCK | | | Successful target | | TTD | Inhibitor | MAPK1 | | | Research target | | TTD | Inhibitor | MET | | | Successful target | | TTD | Inhibitor | PDGFRA | | | Discontinued target | | TTD | Inhibitor | PDGFRB | | | Research target |
|
| Download gene sets |
gmt, text, Detailed text
|
Contact us
Tan Lab , Mail Stop 8117
12801 East 17th Avenue
Division of Medical Oncology , Department of Medicine
University of Colorado School of Medicine
Aurora, CO 80045, USA
* Best viewed in the latest version of Chrome (42+), Safari (8+), IE (11+) or Firefox (35+).
