Tan Lab | DSigDB

Gene Set: D4 : TTD - RO-316233

Collection

D4 : TTD

Chemical Name

RO-316233 ( From PubChem : BISINDOLYLMALEIMIDE IV )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Not	Not	Not	Not	Not	Not	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
327.336 g/mol	3	3	3.5452	True

Structure

InChI

InChI=1S/C20H13N3O2/c24-19-17(13-9-21-15-7-3-1-5-11(13)15)18(20(25)23-19)14-10-22-16-8-4-2-6-12(14)16/h1-10,21-22H,(H,23,24,25)

InChIKey

Links

Gene (29 / 30)

⊖ Less

Source	Type	Unit	Gene	PMID	Other
TTD	Inhibitor		AKT1		Clinical trial target
TTD	Inhibitor		AKT2		Clinical trial target
TTD	Inhibitor		AKT3		Clinical trial target
TTD	Inhibitor		CCNB1		Research target
TTD	Inhibitor		CDK1		Clinical trial target
TTD	Inhibitor		CHEK1		Clinical trial target
TTD	Inhibitor		LCK		Successful target
TTD	Inhibitor		MAPK1		Research target
TTD	Inhibitor		MAPK11		Research target
TTD	Inhibitor		MAPK12		Clinical trial target
TTD	Inhibitor		MAPK14		Clinical trial target
TTD	Inhibitor		MAPK8		Clinical trial target
TTD	Inhibitor		PRKAR1A		Research target
TTD	Inhibitor		PRKCA		Clinical trial target
TTD	Inhibitor		PRKCB		Clinical trial target
TTD	Inhibitor		PRKCD		Clinical trial target
TTD	Inhibitor		PRKCE		Clinical trial target
TTD	Inhibitor		PRKCE		Research target
TTD	Inhibitor		PRKCG		Clinical trial target
TTD	Inhibitor		PRKCQ		Clinical trial target
TTD	Inhibitor		PRKCZ		Research target
TTD	Inhibitor		ROCK1		Clinical trial target
TTD	Inhibitor		RPS6KB1		Discontinued target
TTD	Inhibitor		SGK1		Research target
TTD	Inhibitor		SIRT1		Clinical trial target
PubChem	None	uM	CLK3	-	GI(Protien) :
PubChem	None	uM	PIM1	-	GI(Protien) :
PubChem	None	uM	PIM2	-	GI(Protien) :
PubChem	None	uM	SLK	-	GI(Protien) :
PubChem	None	uM	STK16	-	GI(Protien) :

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