DSigDB Home
Search Gene
Collections
Browse Gene Sets
Download
Help

Gene Set: D4 : TTD - Beta-Lapachone

Collection D4 : TTD
Chemical Name Beta-Lapachone ( From PubChem : BETA-LAPACHONE )
FDA NPC WHO Indian Australia China Traditional
Herbal		 Clinical
Trail
NotNotNotNotNotNotNotNot
Molecular
Weight		 Hydrogen Bond
Donor Count		 Hydrogen Bond
Acceptor Count		 cLogP Lipinski Rule
242.27 g/mol 0 3 2.7521 True
Structure
InChI InChI=1S/C15H14O3/c1-15(2)8-7-11-13(17)12(16)9-5-3-4-6-10(9)14(11)18-15/h3-6H,7-8H2,1-2H3
InChIKey QZPQTZZNNJUOLS-UHFFFAOYSA-N
Links

Gene (24 / 42)


⊖ Less
Source Type Unit Value Gene PMID Assay Other
TTDInhibitorTOP1Successful target
TTDDrug(s)TOP1Successful target
PubChem PotencyuM22.387ATXN2-GI(Protien) :
PubChem PotencyuM25.119BLM-GI(Protien) :
PubChem PotencyuM25.119BLM-GI(Protien) :
PubChem NoneuMCYP1A2-GI(Protien) :
PubChem NoneuMCYP1A2-GI(Protien) :
PubChem PotencyuM3.981CYP2C19-GI(Protien) :
PubChem NoneuMCYP2C19-GI(Protien) :
PubChem PotencyuM31.623CYP2C9-GI(Protien) :
PubChem NoneuMCYP2C9-GI(Protien) :
PubChem PotencyuM15.849CYP2D6-GI(Protien) :
PubChem NoneuMCYP2D6-GI(Protien) :
PubChem PotencyuM15.849CYP3A4-GI(Protien) :
PubChem NoneuMCYP3A4-GI(Protien) :
PubChem PotencyuM14.125EHMT2-GI(Protien) :
PubChem NoneuMGAPDH-GI(Protien) :
PubChem NoneuMHSP90AA1-GI(Protien) :
PubChem PotencyuM5.012MAPT-GI(Protien) :
PubChem PotencyuM11.220MAPT-GI(Protien) :
PubChem PotencyuM12.589MAPT-GI(Protien) :
PubChem PotencyuM19.953MBNL1-GI(Protien) :
PubChem PotencyuM8.912NFKB1-GI(Protien) :
PubChem PotencyuM22.387POLH-GI(Protien) :
PubChem PotencyuM7.943POLI-GI(Protien) :
PubChem PotencyuM8.912POLI-GI(Protien) :
PubChem NoneuMPTGER2-GI(Protien) :
PubChem PotencyuM15.003RGS4-GI(Protien) :
PubChem PotencyuM3.162SMAD3-GI(Protien) :
PubChem PotencyuM2.311TDP1-GI(Protien) :
PubChem PotencyuM2.818TDP1-GI(Protien) :
PubChem PotencyuM5.623TDP1-GI(Protien) :
PubChem PotencyuM1.585THPO-GI(Protien) :
PubChem PotencyuM5.012TP53-GI(Protien) :
PubChem PotencyuM5.012TP53-GI(Protien) :
PubChem PotencyuM5.012USP1-GI(Protien) :
PubChem PotencyuM8.348USP1-GI(Protien) :
PubChem PotencyuM8.912VDR-GI(Protien) :
PubChem PotencyuM11.220VDR-GI(Protien) :
PubChem PotencyuM14.125VDR-GI(Protien) :
PubChem PotencyuM14.125VDR-GI(Protien) :
PubChem PotencyuM31.623VDR-GI(Protien) :
Download gene sets gmt, text, Detailed text
Contact us
Tan Lab , Mail Stop 8117
12801 East 17th Avenue
Division of Medical Oncology , Department of Medicine
University of Colorado School of Medicine
Aurora, CO 80045, USA

* Best viewed in the latest version of Chrome (42+), Safari (8+), IE (11+) or Firefox (35+).