Tan Lab | DSigDB

Gene Set: D4 : TTD - bay 11-7082

Collection

D4 : TTD

Chemical Name

bay 11-7082 ( From PubChem : CASWELL NO. 859A )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Not	Not	Not	Not	Not	Not	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
207.249 g/mol	0	3	2.88678	True

Structure

InChI

InChI=1S/C10H9NO2S/c1-9-3-5-10(6-4-9)14(12,13)8-2-7-11/h2-6,8H,1H3/b8-2+

InChIKey

Links

Gene (16 / 30)

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Source	Type	Unit	Value	Gene	PMID	Other
TTD	Inhibitor			NFKB2		Clinical trial target
TTD	Inhibitor			RELA		Research target
PubChem	Potency	uM	0.056	ALDH1A1	-	GI(Protien) :
PubChem	Potency	uM	0.063	ALDH1A1	-	GI(Protien) :
PubChem	Potency	uM	20.588	ATAD5	-	GI(Protien) :
PubChem	Potency	uM	10.000	ATXN2	-	GI(Protien) :
PubChem	Potency	uM	10.000	ATXN2	-	GI(Protien) :
PubChem	Potency	uM	39.811	CBX1	-	GI(Protien) :
PubChem	Potency	uM	12.589	DRD1	-	GI(Protien) :
PubChem	Potency	uM	1.122	EHMT2	-	GI(Protien) :
PubChem	Potency	uM	1.585	EHMT2	-	GI(Protien) :
PubChem	Potency	uM	12.589	GLS	-	GI(Protien) :
PubChem	Potency	uM	22.387	KAT2A	-	GI(Protien) :
PubChem	None	uM		MITF	-	GI(Protien) :
PubChem	Potency	uM	5.973	RGS4	-	GI(Protien) :
PubChem	None	uM		STK33	-	GI(Protien) :
PubChem	Potency	uM	0.651	TDP1	-	GI(Protien) :
PubChem	Potency	uM	1.300	TDP1	-	GI(Protien) :
PubChem	Potency	uM	3.162	VDR	-	GI(Protien) :
PubChem	Potency	uM	5.623	VDR	-	GI(Protien) :
PubChem	Potency	uM	11.220	VDR	-	GI(Protien) :
ChEMBL	Potency	nM	63.100	ALDH1A1	-	Target : CHEMBL3577
ChEMBL	Potency	nM	56.200	ALDH1A1	-	Target : CHEMBL3577
ChEMBL	Potency	nM	20587.800	ATAD5	-	Target : CHEMBL1741209
ChEMBL	Potency	nM	39810.700	CBX1	-	Target : CHEMBL1741193
ChEMBL	Activity	-		CDK1	-	Target : CHEMBL308
ChEMBL	Potency	nM	12589.300	DRD1	-	Target : CHEMBL2056
ChEMBL	Potency	nM	1122.000	EHMT2	-	Target : CHEMBL6032
ChEMBL	Potency	nM	1584.900	EHMT2	-	Target : CHEMBL6032
ChEMBL	Potency	nM	22387.200	KAT2A	-	Target : CHEMBL5501

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