Tan Lab | DSigDB

Gene Set: D4 : TTD - BAICALEIN

Collection

D4 : TTD

Chemical Name

BAICALEIN ( From PubChem : BAICALEIN )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Not	Not	Not	Not	Not	Not	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
270.237 g/mol	3	5	2.5768	True

Structure

InChI

InChI=1S/C15H10O5/c16-9-6-11(8-4-2-1-3-5-8)20-12-7-10(17)14(18)15(19)13(9)12/h1-7,17-19H

InChIKey

FXNFHKRTJBSTCS-UHFFFAOYSA-N

Links

Gene (44 / 92)

⊖ Less

Source	Type	Unit	Value	Gene	PMID	Other
TTD	Inhibitor			ALOX5		Successful target
TTD	Inhibitor			GLO1		Research target
TTD	Inhibitor			PREP		Research target
TTD	Inhibitor			SELL		Research target
TTD	Inhibitor			SELP		Clinical trial target
TTD	Inhibitor			TNF		Successful target
TTD	Inhibitor			XDH		Successful target
PubChem	None	uM		ABL1	-	GI(Protien) :
PubChem	None	uM		AKR1C4	-	GI(Protien) :
PubChem	Potency	uM	14.989	ALDH1A1	-	GI(Protien) :
PubChem	Potency	uM	1.995	ALOX15	-	GI(Protien) :
PubChem	Potency	uM	15.849	BLM	-	GI(Protien) :
PubChem	None	uM		CASP6	-	GI(Protien) :
PubChem	None	uM		CYP1A2	-	GI(Protien) :
PubChem	None	uM		CYP1A2	-	GI(Protien) :
PubChem	Potency	uM	5.012	CYP2C19	-	GI(Protien) :
PubChem	Potency	uM	5.012	CYP2C9	-	GI(Protien) :
PubChem	Potency	uM	31.623	CYP2D6	-	GI(Protien) :
PubChem	Potency	uM	31.623	CYP3A4	-	GI(Protien) :
PubChem	None	uM		CYP3A4	-	GI(Protien) :
PubChem	Potency	uM	17.783	FEN1	-	GI(Protien) :
PubChem	Potency	uM	35.481	FEN1	-	GI(Protien) :
PubChem	None	uM		GAPDH	-	GI(Protien) :
PubChem	Potency	uM	3.162	HPGD	-	GI(Protien) :
PubChem	Potency	uM	7.943	HPGD	-	GI(Protien) :
PubChem	Potency	uM	28.184	HPGD	-	GI(Protien) :
PubChem	None	uM		HPGD	-	GI(Protien) :
PubChem	Potency	uM	15.849	L3MBTL1	-	GI(Protien) :
PubChem	Potency	uM	7.943	MAPT	-	GI(Protien) :
PubChem	Potency	uM	10.000	MAPT	-	GI(Protien) :
PubChem	Potency	uM	25.119	MAPT	-	GI(Protien) :
PubChem	Potency	uM	28.184	MAPT	-	GI(Protien) :
PubChem	None	uM		MAPT	-	GI(Protien) :
PubChem	None	uM		NR0B1	-	GI(Protien) :
PubChem	None	uM		NR0B1	-	GI(Protien) :
PubChem	None	uM		NR5A1	-	GI(Protien) :
PubChem	None	uM		PLA2G7	-	GI(Protien) :
PubChem	None	uM		PLA2G7	-	GI(Protien) :
PubChem	Potency	uM	3.162	POLH	-	GI(Protien) :
PubChem	Potency	uM	15.101	POLH	-	GI(Protien) :
PubChem	Potency	uM	1.413	POLK	-	GI(Protien) :
PubChem	Potency	uM	1.778	POLK	-	GI(Protien) :
PubChem	Potency	uM	2.239	POLK	-	GI(Protien) :
PubChem	Potency	uM	19.953	POLK	-	GI(Protien) :
PubChem	None	uM		PSIP1	-	GI(Protien) :
PubChem	None	uM		PSIP1	-	GI(Protien) :
PubChem	None	uM		RIN1	-	GI(Protien) :
PubChem	None	uM		SMARCA2	-	GI(Protien) :
PubChem	None	uM		SMARCA2	-	GI(Protien) :
PubChem	Potency	uM	11.886	TDP1	-	GI(Protien) :
PubChem	Potency	uM	16.789	TDP1	-	GI(Protien) :
PubChem	Potency	uM	29.855	TDP1	-	GI(Protien) :
PubChem	Potency	uM	44.668	THRB	-	GI(Protien) :
PubChem	Potency	uM	0.631	TP53	-	GI(Protien) :
PubChem	None	uM		TRA	-	GI(Protien) :
PubChem	None	uM		TRA	-	GI(Protien) :
ChEMBL	Potency	nM	14988.900	ALDH1A1	-	Target : CHEMBL3577
ChEMBL	Potency	nM	1995.300	ALOX15	-	Target : CHEMBL2903
ChEMBL	Activity	-		ALOX15	-	Target : CHEMBL2903
ChEMBL	Potency	nM	631.000	APEX1	-	Target : CHEMBL5619
ChEMBL	Potency	nM	15848.900	BLM	-	Target : CHEMBL1293237
ChEMBL	AC50	nM	501.190	CYP1A2	-	Target : CHEMBL3356
ChEMBL	Potency	nM	5011.900	CYP2C19	-	Target : CHEMBL3622
ChEMBL	Potency	nM	5011.900	CYP2C9	-	Target : CHEMBL3397
ChEMBL	Potency	nM	31622.800	CYP2D6	-	Target : CHEMBL289
ChEMBL	Potency	nM	31622.800	CYP3A4	-	Target : CHEMBL340
ChEMBL	AC50	nM	31622.800	CYP3A4	-	Target : CHEMBL340
ChEMBL	Inhibition	-		EGLN1	-	Target : CHEMBL5697
ChEMBL	Activity	-		EGLN1	-	Target : CHEMBL5697
ChEMBL	Activity	-		GPR35	-	Target : CHEMBL1293267
ChEMBL	Inhibition	-		HIF1AN	-	Target : CHEMBL5909
ChEMBL	Potency	nM	3162.300	HPGD	-	Target : CHEMBL1293255
ChEMBL	Potency	nM	28183.800	HPGD	-	Target : CHEMBL1293255
ChEMBL	Potency	nM	7943.300	HPGD	-	Target : CHEMBL1293255
ChEMBL	Potency	nM	2511.900	HSD17B10	-	Target : CHEMBL4159
ChEMBL	Potency	nM	3981.100	HSD17B10	-	Target : CHEMBL4159
ChEMBL	Potency	nM	1995.300	HSD17B10	-	Target : CHEMBL4159
ChEMBL	Potency	nM	12589.300	KDM4E	-	Target : CHEMBL1293226
ChEMBL	Potency	nM	891.300	KDM4E	-	Target : CHEMBL1293226
ChEMBL	Potency	nM	7079.500	KDM4E	-	Target : CHEMBL1293226
ChEMBL	Potency	nM	15848.900	L3MBTL1	-	Target : CHEMBL1287622
ChEMBL	Potency	nM	7943.300	MAPT	-	Target : CHEMBL1293224
ChEMBL	Potency	nM	28183.800	MAPT	-	Target : CHEMBL1293224
ChEMBL	Potency	nM	25118.900	MAPT	-	Target : CHEMBL1293224
ChEMBL	Potency	nM	10000.000	MAPT	-	Target : CHEMBL1293224
ChEMBL	Activity	-		MGAM	-	Target : CHEMBL2074
ChEMBL	Activity	-		NR3C1	-	Target : CHEMBL2034
ChEMBL	Potency	nM	5011.900	RECQL	-	Target : CHEMBL1293236
ChEMBL	Potency	nM	28183.800	RECQL	-	Target : CHEMBL1293236
ChEMBL	Potency	nM	15848.900	RECQL	-	Target : CHEMBL1293236
ChEMBL	Potency	nM	44668.400	THRB	-	Target : CHEMBL1947
ChEMBL	Potency	nM	631.000	TP53	-	Target : CHEMBL4096

Download gene sets

gmt, text, Detailed text