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Gene Set: D4 : TTD - AZD1480


Collection D4 : TTD
Chemical Name AZD1480 ( From PubChem : AZD1480 )
FDA NPC WHO Indian Australia China Traditional
Herbal
Clinical
Trail
NotNotNotNotNotNotNotNot
Molecular
Weight
Hydrogen Bond
Donor Count
Hydrogen Bond
Acceptor Count
cLogP Lipinski Rule
348.766 g/mol 3 6 3.1533 True
Structure
InChI InChI=1S/C14H14ClFN8/c1-7-3-11(24-23-7)21-13-10(15)6-19-14(22-13)20-8(2)12-17-4-9(16)5-18-12/h3-6,8H,1-2H3,(H3,19,20,21,22,23,24)/t8-/m0/s1
InChIKey PDOQBOJDRPLBQU-QMMMGPOBSA-N
Links

Gene (5 / 8)


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Source Type Unit Value Gene PMID Assay Other
TTDDrug(s)JAK1Clinical trial target
TTDDrug(s)JAK2Clinical trial target
PubChem PotencyuM0.772YES1GI(Protien) :
ChEMBLInhibition-STAT3
-Target : CHEMBL4026
ChEMBLActivity-STAT3
-Target : CHEMBL4026
ChEMBLActivity-STAT5A
-Target : CHEMBL5403
ChEMBLActivity-STAT5A
-Target : CHEMBL5403
ChEMBLInhibition-STAT5A
-Target : CHEMBL5403
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