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Gene Set: D4 : TTD - Axitinib

Collection D4 : TTD
Chemical Name Axitinib ( From PubChem : AXITINIB )
FDA NPC WHO Indian Australia China Traditional
Herbal		 Clinical
Trail
ApprovedNotNotNotNotNotNotNot
Molecular
Weight		 Hydrogen Bond
Donor Count		 Hydrogen Bond
Acceptor Count		 cLogP Lipinski Rule
386.47 g/mol 2 5 5.03 False(3/4)
Structure
InChI InChI=1S/C22H18N4OS/c1-23-22(27)18-7-2-3-8-21(18)28-16-10-11-17-19(25-26-20(17)14-16)12-9-15-6-4-5-13-24-15/h2-14H,1H3,(H,23,27)(H,25,26)/b12-9+
InChIKey RITAVMQDGBJQJZ-FMIVXFBMSA-N
Links

Gene (7 / 15)


⊖ Less
Source Type Unit Value Gene PMID Assay Other
TTDMultitargetCSF1Clinical trial target
TTDInhibitorCSF1Clinical trial target
TTDDrug(s)CSF1Clinical trial target
TTDMultitargetKDRSuccessful target
TTDInhibitorKDRSuccessful target
TTDDrug(s)KDRSuccessful target
PubChem AhR Potency (uM)uM2.282AHR-GI(Protien) :
PubChem Potency-Replicate_1uM3.758AHR-GI(Protien) :
PubChem Potency-Replicate_1uM0.084ESR1-GI(Protien) :
PubChem Potency-Replicate_1uM6.740ESR1-GI(Protien) :
PubChem Ratio Potency (uM)uM9.893ESR1-GI(Protien) :
PubChem Ratio Potency (uM)uM4.057NFE2L2-GI(Protien) :
PubChem PotencyuM2.661TDP1-GI(Protien) :
PubChem PotencyuM4.217TDP1-GI(Protien) :
PubChem PotencyuM0.688YES1GI(Protien) :
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