Tan Lab | DSigDB

Gene Set: D4 : TTD - Artemisinin

Collection

D4 : TTD

Chemical Name

Artemisinin ( From PubChem : ARTEMISININ )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Not	Not	Not	Not	Not	Not	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
282.332 g/mol	0	5	2.3949	True

Structure

InChI

InChI=1S/C15H22O5/c1-8-4-5-11-9(2)12(16)17-13-15(11)10(8)6-7-14(3,18-13)19-20-15/h8-11,13H,4-7H2,1-3H3

InChIKey

Links

Gene (7 / 18)

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Source	Type	Unit	Value	Gene	PMID	Other
TTD	Inhibitor			DHODH		Successful target
TTD	Drug(s)			DHODH		Successful target
PubChem	None	uM		DRD2	-	GI(Protien) :
PubChem	Potency	uM	0.841	TDP1	-	GI(Protien) :
PubChem	None	uM		DRD2	-	GI(Protien) :
PubChem	Potency	uM	0.651	TDP1	-	GI(Protien) :
PubChem	Potency	uM	4.109	TDP1	-	GI(Protien) :
PubChem	Potency	uM	25.119	ALDH1A1	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	1.333	AR	-	GI(Protien) :
PubChem	AR Potency (uM)	uM	1.385	AR	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	1.693	AR	-	GI(Protien) :
PubChem	Ratio Potency (uM)	uM	1.345	ESR1	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	1.900	ESR1	-	GI(Protien) :
PubChem	Potency	uM	3.162	HTT	-	GI(Protien) :
PubChem	Potency	uM	0.231	TDP1	-	GI(Protien) :
PubChem	Potency	uM	0.291	TDP1	-	GI(Protien) :
ChEMBL	Potency	nM	3162.300	HTT	-	Target : CHEMBL5514
ChEMBL	Potency	nM	25118.900	ALDH1A1	-	Target : CHEMBL3577

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