Tan Lab | DSigDB

Gene Set: D4 : TTD - Arachidonic acid

Collection

D4 : TTD

Chemical Name

Arachidonic acid ( From PubChem : ARACHIDONIC ACID )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Not	Not	Not	Not	Not	Not	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
304.467 g/mol	1	2	6.2167	False(3/4)

Structure

InChI

InChI=1S/C20H32O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20(21)22/h6-7,9-10,12-13,15-16H,2-5,8,11,14,17-19H2,1H3,(H,21,22)/b7-6-,10-9-,13-12-,16-15-

InChIKey

YZXBAPSDXZZRGB-DOFZRALJSA-N

Links

Gene (17 / 35)

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Source	Type	Unit	Value	Gene	PMID	Other
TTD	Activator			CLCN2		Successful target
PubChem	Potency	uM	2.818	ALDH1A1	-	GI(Protien) :
PubChem	Potency	uM	7.943	ALDH1A1	-	GI(Protien) :
PubChem	Potency	uM	0.079	ALOX15	-	GI(Protien) :
PubChem	Potency	uM	0.316	ALOX15	-	GI(Protien) :
PubChem	Potency	uM	15.849	EHMT2	-	GI(Protien) :
PubChem	None	uM		GFER	-	GI(Protien) :
PubChem	Potency	uM	15.849	HPGD	-	GI(Protien) :
PubChem	Potency	uM	22.387	KAT2A	-	GI(Protien) :
PubChem	Potency	uM	12.589	MAPT	-	GI(Protien) :
PubChem	Potency	uM	28.184	MAPT	-	GI(Protien) :
PubChem	None	uM		OXTR	-	GI(Protien) :
PubChem	None	uM		PLA2G7	-	GI(Protien) :
PubChem	Potency	uM	12.589	POLK	-	GI(Protien) :
PubChem	Potency	uM	15.849	POLK	-	GI(Protien) :
PubChem	Potency	uM	11.582	TDP1	-	GI(Protien) :
PubChem	Potency	uM	23.715	TDP1	-	GI(Protien) :
PubChem	Potency	uM	29.855	TDP1	-	GI(Protien) :
PubChem	Potency	uM	50.119	USP1	-	GI(Protien) :
PubChem	Potency	uM	5.623	VDR	-	GI(Protien) :
PubChem	Potency	uM	7.943	VDR	-	GI(Protien) :
ChEMBL	Potency	nM	2818.400	ALDH1A1	-	Target : CHEMBL3577
ChEMBL	Potency	nM	7943.300	ALDH1A1	-	Target : CHEMBL3577
ChEMBL	Potency	nM	79.400	ALOX15	-	Target : CHEMBL2903
ChEMBL	Potency	nM	316.200	ALOX15	-	Target : CHEMBL2903
ChEMBL	Potency	nM	15848.900	EHMT2	-	Target : CHEMBL6032
ChEMBL	Potency	nM	15848.900	HPGD	-	Target : CHEMBL1293255
ChEMBL	Potency	nM	3981.100	HSD17B10	-	Target : CHEMBL4159
ChEMBL	Potency	nM	1995.300	HSD17B10	-	Target : CHEMBL4159
ChEMBL	Potency	nM	22387.200	KAT2A	-	Target : CHEMBL5501
ChEMBL	Potency	nM	28183.800	KDM4E	-	Target : CHEMBL1293226
ChEMBL	Potency	nM	25118.900	KDM4E	-	Target : CHEMBL1293226
ChEMBL	Potency	nM	12589.300	MAPT	-	Target : CHEMBL1293224
ChEMBL	Potency	nM	28183.800	MAPT	-	Target : CHEMBL1293224
ChEMBL	Potency	nM	2238.700	RECQL	-	Target : CHEMBL1293236

Download gene sets

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