Tan Lab | DSigDB

Gene Set: D4 : TTD - Dihydrotestosterone

Collection

D4 : TTD

Chemical Name

Dihydrotestosterone ( From PubChem : ANDROSTANOLONE )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Not	Not	Not	Approved	Not	Not	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
290.44 g/mol	1	2	3.9591	True

Structure

InChI

InChI=1S/C19H30O2/c1-18-9-7-13(20)11-12(18)3-4-14-15-5-6-17(21)19(15,2)10-8-16(14)18/h12,14-17,21H,3-11H2,1-2H3/t12-,14-,15-,16-,17-,18-,19-/m0/s1

InChIKey

Links

Gene (8 / 28)

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Source	Type	Unit	Value	Gene	PMID	Other
TTD	Inhibitor			AR		Successful target
TTD	Inhibitor			HSD17B1		Research target
PubChem	Potency-Replicate_1	uM	0.001	AR	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	0.003	AR	-	GI(Protien) :
PubChem	Ratio Potency (uM)	uM	0.003	AR	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	0.005	AR	-	GI(Protien) :
PubChem	Ratio Potency (uM)	uM	0.006	AR	-	GI(Protien) :
PubChem	Potency	uM	0.007	AR	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM		AR	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	0.076	ESR1	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	0.422	ESR1	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	0.431	ESR1	-	GI(Protien) :
PubChem	Potency	uM	0.447	ESR1	-	GI(Protien) :
PubChem	Ratio Potency (uM)	uM	0.658	ESR1	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	0.849	ESR1	-	GI(Protien) :
PubChem	Ratio Potency (uM)	uM	1.396	ESR1	-	GI(Protien) :
PubChem	Potency	uM	24.337	NFE2L2	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	26.973	NFE2L2	-	GI(Protien) :
PubChem	Ratio Potency (uM)	uM	28.571	NFE2L2	-	GI(Protien) :
PubChem	None	uM		NLRP3	-	GI(Protien) :
PubChem	None	uM		NLRP3	-	GI(Protien) :
PubChem	None	uM		NLRP3	-	GI(Protien) :
PubChem	None	uM		NR1H4	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	6.092	NR3C1	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	8.485	NR3C1	-	GI(Protien) :
PubChem	Potency	uM	10.000	NR3C1	-	GI(Protien) :
PubChem	None	uM		NR3C1	-	GI(Protien) :
PubChem	Potency	uM	7.943	RXRA	-	GI(Protien) :

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