Tan Lab | DSigDB

Gene Set: D4 : TTD - 1-Naphthalen-1-yl-piperazine

Collection

D4 : TTD

Chemical Name

1-Naphthalen-1-yl-piperazine ( From PubChem : 1-NAPHTHYLPIPERAZINE )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Not	Not	Not	Not	Not	Not	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
212.29 g/mol	1	2	2.6432	True

Structure

InChI

InChI=1S/C14H16N2/c1-2-6-13-12(4-1)5-3-7-14(13)16-10-8-15-9-11-16/h1-7,15H,8-11H2

InChIKey

Links

Gene (12 / 28)

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Source	Type	Unit	Value	Gene	PMID	Other
TTD	Inhibitor			HTR1A		Successful target
TTD	Inhibitor			HTR1D		Successful target
TTD	Inhibitor			HTR6		Clinical trial target
TTD	Inhibitor			HTR7		Research target
PubChem	None	uM		CYP1A2	-	GI(Protien) :
PubChem	None	uM		CYP1A2	-	GI(Protien) :
PubChem	Potency	uM	15.849	CYP2D6	-	GI(Protien) :
PubChem	None	uM		CYP2D6	-	GI(Protien) :
PubChem	Potency	uM	16.834	EHMT2	-	GI(Protien) :
PubChem	None	uM		HTR1A		GI(Protien) :
PubChem	None	uM		HTR1B		GI(Protien) :
PubChem	None	uM		HTR1B		GI(Protien) :
PubChem	None	uM		HTR1B		GI(Protien) :
PubChem	None	uM		HTR1D		GI(Protien) :
PubChem	None	uM		HTR1D		GI(Protien) :
PubChem	None	uM		HTR1E		GI(Protien) :
PubChem	None	uM		HTR1E		GI(Protien) :
PubChem	None	uM		HTR1E		GI(Protien) :
PubChem	None	uM		HTR1F		GI(Protien) :
PubChem	None	uM		HTR1F		GI(Protien) :
PubChem	None	uM		HTR2B		GI(Protien) :
PubChem	None	uM		HTR2B		GI(Protien) :
PubChem	None	uM		HTR7		GI(Protien) :
PubChem	Potency	uM	18.356	TDP1	-	GI(Protien) :
ChEMBL	AC50	nM	10000.000	CYP1A2	-	Target : CHEMBL3356
ChEMBL	AC50	nM	15848.900	CYP2D6	-	Target : CHEMBL289
ChEMBL	Potency	nM	15848.900	CYP2D6	-	Target : CHEMBL289
ChEMBL	Potency	nM	16833.600	EHMT2	-	Target : CHEMBL6032

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