Tan Lab | DSigDB

Gene Set: D4 : TTD - Amcinonide

Collection

D4 : TTD

Chemical Name

Amcinonide ( From PubChem : AMCINONIDE )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Approved	Not	Not	Not	Not	Not	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
502.572 g/mol	1	7	3.5238	False(3/4)

Structure

InChI

InChI=1S/C28H35FO7/c1-16(30)34-15-22(33)28-23(35-26(36-28)9-4-5-10-26)13-20-19-7-6-17-12-18(31)8-11-24(17,2)27(19,29)21(32)14-25(20,28)3/h8,11-12,19-21,23,32H,4-7,9-10,13-15H2,1-3H3/t19-,20-,21-,23+,24-,25-,27-,28+/m0/s1

InChIKey

ILKJAFIWWBXGDU-MOGDOJJUSA-N

Links

Gene (11 / 18)

⊖ Less

Source	Type	Unit	Value	Gene	PMID	Other
TTD	Agonist			NR3C1		Successful target
TTD	Drug(s)			NR3C1		Successful target
PubChem	None	uM		ADAM17	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	0.011	AR	-	GI(Protien) :
PubChem	None	uM		CFTR	-	GI(Protien) :
PubChem	Potency	uM	0.259	GMNN	-	GI(Protien) :
PubChem	Potency	uM	0.001	HIF1A	-	GI(Protien) :
PubChem	Potency	uM	7.080	IDH1	-	GI(Protien) :
PubChem	Potency	uM	14.125	IDH1	-	GI(Protien) :
PubChem	None	uM		MAP4K2	-	GI(Protien) :
PubChem	Potency	uM	3.981	NPSR1	-	GI(Protien) :
PubChem	Ratio Potency (uM)	uM	0.012	NR3C1	-	GI(Protien) :
PubChem	None	uM		NR3C1	-	GI(Protien) :
PubChem	None	uM		STAT1	-	GI(Protien) :
PubChem	Potency	uM	2.311	TDP1	-	GI(Protien) :
PubChem	Potency	uM	4.611	TDP1	-	GI(Protien) :
ChEMBL	Potency	nM	1.300	HIF1A	-	Target : CHEMBL4261
ChEMBL	Potency	nM	3981.100	NPSR1	-	Target : CHEMBL5162

Download gene sets

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